DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10565 and DNAJC4

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_001294909.1	Gene:	DNAJC4 / 3338	HGNCID:	5271	Length:	249	Species:	Homo sapiens

Alignment Length:	172	Identity:	37/172 - (21%)
Similarity:	68/172 - (39%)	Gaps:	40/172 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 HYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEILGTSKPR 141
            :|.:||   :...||.::|:||:.......|||  :..|...:.  ..|..:::||.:|...:.|
Human    35 YYELLG---VHPGASTEEVKRAFFSKSKELHPD--RDPGNPSLH--SRFVELSEAYRVLSREQSR 92

  Fly   142 RSFDSVDPEFDDSLPSQNDIDNDYFGVFNK--FFTLNGRW------------SEKPHVPSFGQVD 192
            ||       :||.|.|.:...:....|.:|  ..|.:..|            |.:|..|...|..
Human    93 RS-------YDDQLRSGSPPKSPRTTVHDKSAHQTHSSSWTPPNAQYWSQFHSVRPQGPQLRQQQ 150

  Fly   193 AKREEVERFYNF----------WYDFKSWRE--FSYLDEEDK 222
            .|:.:....|..          :..|:..::  .:::||:|:
Human   151 HKQNKQVLGYCLLLMLAGMGLHYIAFRKVKQMHLNFMDEKDR 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	37/172 (22%)
		DnaJ	76..145	CDD:278647	19/67 (28%)
		RILP-like	268..>344	CDD:304877
		RAC_head	332..401	CDD:293322
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
DNAJC4	NP_001294909.1	DnaJ	34..96	CDD:278647	19/74 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156723
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930