DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10565 and zuo1

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_596284.2	Gene:	zuo1 / 2539801	PomBaseID:	SPBC1778.01c	Length:	442	Species:	Schizosaccharomyces pombe

Alignment Length:	428	Identity:	160/428 - (37%)
Similarity:	232/428 - (54%)	Gaps:	47/428 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TVATAVEVQL-------PLKVVRRKIERVGFAYFAQ-RRQ-----FLAPGGVE---RSESDEKLE 53
            |...|:|...       ||  ::|.:|.||..:.|. |||     |.....:|   :.:.:.|.|
pombe    13 TTKQAIEASFVPHGKISPL--IKRAVEPVGPLFLAHARRQRHGRTFSEDERLEVKNKVQEEVKEE 75

  Fly    54 GVGEEVDISYLKSLDPKEWKDQDHYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEV 118
            ...||.|.:.|:: ||||||.|||||||||.|.||:|..:.:::|:.:.||.|||||:.|.|.
pombe    76 SEDEEEDPAMLRA-DPKEWKQQDHYAVLGLSKYRYKADTEQIKKAHLKKVLKHHPDKKAASGN-- 137

  Fly   119 IQDDDYFTCITKAYEILGTSKPRRSFDSVDPEFDDSLPSQNDIDNDYFGVFNKFFTLNGRWSEKP 183
            |.||.:|.||.||||||.....||.||||| |..|..|.::.....:|.::...|....|:|:|.
pombe   138 INDDSFFKCIQKAYEILSDPVRRRQFDSVD-ENADVEPPESTTKETFFELWTPVFESEARFSKKQ 201

  Fly   184 HVPSFGQVDAKREEVERFYNFWYDFKSWREFSYLDEEDKEKGQDRDERRWIEKENRAARIKRKKE 248
            .|||.|.:::.|.||:.||||||:|.|||.|.|||::..:.|:.||.:|:.||:||:.|.|.|..
pombe   202 PVPSLGTIESTRAEVDNFYNFWYNFDSWRSFEYLDKDIPDDGESRDNKRFQEKKNRSERQKNKAR 266

  Fly   249 EMSRIRSLVDLAYNNDKRIQRFKQEEKDRKAAAK-------RAKMDAAQAQKAEADRAIREAALA 306
            :.:|:|:|||.|..:|.||:.||::||..|||.|       |....|||.:|.|.:|...|.|.|
pombe   267 DNARLRNLVDTALASDPRIKLFKEQEKAAKAARKWEREAGAREAAAAAQKKKEEEERRAAEEAAA 331

  Fly   307 KEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKDCKYYAKNDKDQLKHMEGTEKICETF- 370
            |..|..|.:|       .:|.:||..|:::|.:::.:||..|::..|....:|::...|..:..
pombe   332 KASAAAANKK-------AKEDKKKAQKRDKKVVKNALKDFNYFSATDVPSAEHVDSVLKDVDVIM 389

  Fly   371 ------NLAELQALNKAMESKGRESFVAALQTAEQKIA 402
                  .|.:|.|...|.::.|    .|::|....|.|
pombe   390 SKLGEGELGQLAADINAEKAAG----AASVQAVFDKFA 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	97/205 (47%)
		DnaJ	76..145	CDD:278647	36/68 (53%)
		RILP-like	268..>344	CDD:304877	27/82 (33%)
		RAC_head	332..401	CDD:293322	15/75 (20%)
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
zuo1	NP_596284.2	ZUO1	82..441	CDD:227594	141/357 (39%)
		DnaJ	97..164	CDD:278647	36/68 (53%)
		RAC_head	356..432	CDD:293322	15/72 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	131	1.000	Domainoid score	I1322
eggNOG	1	0.900	-	-		E1_KOG0724
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31656
Inparanoid	1	1.050	252	1.000	Inparanoid score	I774
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004281
OrthoInspector	1	1.000	-	-		oto101656
orthoMCL	1	0.900	-	-		OOG6_102149
Panther	1	1.100	-	-	LDO	PTHR43999
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2016
SonicParanoid	1	1.000	-	-		X3017
TreeFam	1	0.960	-	-
	13	12.850