Protein Alignment CG10565 and DNAJC21

DIOPT Version :9

• Sequence 1: NP_001246856.1
• Gene: CG10565 / 40332
• FlyBaseID: FBgn0037051
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: XP_011512267.2
• Gene: DNAJC21 / 134218
• HGNCID: 27030
• Length: 676
• Species: Homo sapiens
• Alignment Length: 600
• Identity: 135/600 - (22%)
• Similarity: 216/600 - (36%)
• Gaps: 178/600 - (29%)

  Fly    77 HYAVLGLGKLRYEASEDDVRRAYRRMVLLHHPDKRKAKGEEVIQDDDYFTCITKAYEILGTSKPR 141
            ||..||   :|.:|||:::::|||::.|..||||......|..:.   |..|..||::|...:.|
Human    91 HYEALG---VRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQ---FKLIQAAYDVLSDPQER 149

  Fly   142 RSFDS---------VDPEF-DDSL-----------PSQNDIDNDYFGVFNKFFTLNGR------- 178
            ..:|:         .|.|: ||||           ....|.:..::.|:...|.:..:
Human   150 AWYDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELESVL 214

  Fly   179 WSEKPHVPSFGQVDAKREE-VERFYNFWYDFKSWREFSYLDEEDKEKGQDRDERRWIEKENRAAR 242
            ..|....|:||...:..:. |..||.:|..|.:.:.|::.:|.|..:..:|.|:|.:||||:..|
Human   215 EEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKEEYDTRQASNRWEKRAMEKENKKIR 279

  Fly   243 IKRKKEEMSRIRSLVDLAYNNDKRIQRFKQ------EEKDRKAAAKRAKMDAAQAQKAEADRA-- 299
            .|.:||:...:|.||......|||:|..::      .||.|||...|.:....||:..|..|.
Human   280 DKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQKLKQAKLVEQYREQS 344

  Fly   300 -IREAALAKE--KAEKAEQKRIEQIRIEREQQKKLLKKERKTL-RDKVKDCKYY----------- 349
             :..|.|.||  :.|...:|.......|.|.::..||.|.... .|:.:|.:.|
Human   345 WMTMANLEKELQEMEARYEKEFGDGSDENEMEEHELKDEEDGKDSDEAEDAELYDDLYCPACDKS 409

  Fly   350 ------AKNDKDQLKHME----------------------------GTEKICE----------TF 370
                  .||.:...||.|                            .:|:..|          ||
Human   410 FKTEKAMKNHEKSKKHREMVALLKQQLEEEEENFSRPQIDENPLDDNSEEEMEDAPKQKVKYLTF 474

  Fly   371 NLAELQALNKAMESK---------GRESFVAALQ-----------------TAEQKIAAELEE-- 407
            .......|:|..:.|         |::|::.|..                 .:|.|.|..|.|
Human   475 RFIFALRLSKKQKKKKQKPAQDVPGKDSYLPAAHFQMAWGKKCVLGERRDGESEHKCAKMLLENR 539

  Fly   408 ------------------------INQTQAKKLASSAATPKGVKEV------KKNELWS-----N 437
                                    :||..||:|..|......|.|:      .|:|..|     .
Human   540 QNYDDNFNVNGPGEGVKVDPEDTNLNQDSAKELEDSPQENVSVTEIIKPCDDPKSEAKSVPKPKG 604

  Fly   438 ENVQLLIKAVNLFPAGTAQRWDVIATFINQHS--PDNTVLVNARDVLNKAKALQNTDHSKSSLKT 500
            :..:.:.|.|.: || ..|...|:.:....||  |....|.:         .|:.|.|:::...:
Human   605 KKTKDMKKPVRV-PA-EPQTMSVLISCTTCHSEFPSRNKLFD---------HLKATGHARAPSSS 658

  Fly   501 QANDAAFASFEKSKK 515
            ..|.|..:..:|.|:
Human   659 SLNSATSSQSKKEKR 673

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	68/239 (28%)
		DnaJ	76..145	CDD:278647	23/67 (34%)
		RILP-like	268..>344	CDD:304877	23/87 (26%)
		RAC_head	332..401	CDD:293322	22/150 (15%)
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
DNAJC21	XP_011512267.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156740
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840