DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10565 and Dnajc3

DIOPT Version :9

Sequence 1:	NP_001246856.1	Gene:	CG10565 / 40332	FlyBaseID:	FBgn0037051	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_032955.2	Gene:	Dnajc3 / 100037258	MGIID:	107373	Length:	504	Species:	Mus musculus

Alignment Length:	452	Identity:	96/452 - (21%)
Similarity:	163/452 - (36%)	Gaps:	136/452 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 AYFAQRRQFLAPGGVERSESDEKLEGVGEEVDISYLKSLDPKEWKDQDHYAVLGLGKLRYEASED 93
            ||:.:...|||.|     :|...|..:.:.:.:    .:|....:.|..:.:|..|||  :.:||
Mouse    73 AYYRRATVFLAMG-----KSKAALPDLTKVIAL----KMDFTAARLQRGHLLLKQGKL--DEAED 126

  Fly    94 DVRRAYRRMVLLHHP---DKRKAKGEEVIQDD---------------DYFTCIT---KAYEI--- 134
            |.::     ||..:|   ::::|:.:.|..|:               ||...||   |..|:
Mouse   127 DFKK-----VLKSNPSEQEEKEAESQLVKADEMQRLRSQALDAFDGADYTAAITFLDKILEVCVW 186

  Fly   135 ------------LGTSKPRRSFDSVDPEFDDSLPSQNDIDNDYFGVFNKFFTLNGRWSEKPHVPS 187
                        :...:||::.        ..|.:.:.:.:|....|.|..||..:..:  |..|
Mouse   187 DAELRELRAECFIKEGEPRKAI--------SDLKAASKLKSDNTEAFYKISTLYYQLGD--HELS 241

  Fly   188 FGQVDAKREEVERFYNFWYDFKSWREFSYLDEEDK----EKGQDRDERRWIEKENRAARIKRKKE 248
            ..:|                    ||...||::.|    ...|.:...:.||......|..|..:
Mouse   242 LSEV--------------------RECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTD 286

  Fly   249 EMSRIRSLV-------DLAYNNDKRI-QRFKQEEKDRKAAA------------KRAKMDAAQAQK 293
            ..|:..|::       :....:.:|| ..|.::||..:|..            ..|..|.|:|..
Mouse   287 ATSKYESVMKTEPSVAEYTVRSKERICHCFSKDEKPVEAIRICSEVLQMEPDNVNALKDRAEAYL 351

  Fly   294 AEA--DRAIREAALAKEKAEKAEQKRIEQIRIEREQQKKLLKKERKTLRDKVKDCKYYAKNDKDQ 356
            .|.  |.||::...|:|..|..     :|||...|:.::|||:.:|  ||      ||
Mouse   352 IEEMYDEAIQDYEAAQEHNEND-----QQIREGLEKAQRLLKQSQK--RD------YY------- 396

  Fly   357 LKHMEGTEKICETFNLAELQALNKAMESKGRESFVAALQTAEQKIAAELEEINQTQAKKLAS 418
                    ||......|:.|.:.||......:......|..|:|..||.:.|:...||::.|
Mouse   397 --------KILGVKRNAKKQEIIKAYRKLALQWHPDNFQNEEEKKKAEKKFIDIAAAKEVLS 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10565	NP_001246856.1	CbpA	76..282	CDD:225124	48/265 (18%)
		DnaJ	76..145	CDD:278647	21/104 (20%)
		RILP-like	268..>344	CDD:304877	25/89 (28%)
		RAC_head	332..401	CDD:293322	15/68 (22%)
		SANT	584..633	CDD:197842
		SANT	585..632	CDD:238096
Dnajc3	NP_032955.2	TPR_11	36..100	CDD:290150	8/31 (26%)
		TPR 1	37..70
		TPR repeat	37..65	CDD:276809
		TPR repeat	70..100	CDD:276809	8/31 (26%)
		TPR 2	72..104		8/39 (21%)
		TPR_11	73..136	CDD:290150	19/78 (24%)
		TPR 3	105..138		11/39 (28%)
		TPR repeat	105..133	CDD:276809	9/34 (26%)
		TPR_1	107..137	CDD:278916	10/36 (28%)
		TPR_11	153..217	CDD:290150	9/71 (13%)
		TPR 4	154..187		6/32 (19%)
		TPR repeat	157..182	CDD:276809	5/24 (21%)
		TPR_11	187..252	CDD:290150	13/94 (14%)
		TPR repeat	187..217	CDD:276809	3/37 (8%)
		TPR 5	188..221		3/40 (8%)
		TPR 6	222..255		11/54 (20%)
		TPR repeat	222..250	CDD:276809	9/49 (18%)
		TPR repeat	256..280	CDD:276809	4/23 (17%)
		TPR 7	268..301		6/32 (19%)
		TPR repeat	301..335	CDD:276809	6/33 (18%)
		TPR 8	306..339		6/32 (19%)
		TPR_19	318..382	CDD:291240	17/68 (25%)
		TPR 9	340..373		11/32 (34%)
		TPR_1	340..373	CDD:278916	11/32 (34%)
		TPR repeat	340..368	CDD:276809	9/27 (33%)
		TPR repeat	374..397	CDD:276809	12/45 (27%)
		Flexible linker. /evidence=ECO:0000250	375..393		8/19 (42%)
		DnaJ	392..>498	CDD:223560	20/82 (24%)
		DnaJ	394..459	CDD:278647	18/78 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	451..481		96/452 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847144
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930