Protein Alignment ICA69 and Ica1l

DIOPT Version :9

• Sequence 1: NP_001246855.1
• Gene: ICA69 / 40331
• FlyBaseID: FBgn0037050
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_036009489.1
• Gene: Ica1l / 70375
• MGIID: 1917625
• Length: 452
• Species: Mus musculus
• Alignment Length: 426
• Identity: 158/426 - (37%)
• Similarity: 216/426 - (50%)
• Gaps: 55/426 - (12%)

  Fly     4 SEVQHQFWITKKVVQRKLGTKEDKHIISSDAELDSKIEVFKSISDTSLNLCKIIDQYQERLCILS 68
            |.:|..:|.||:|..:..|.|||:|:::||||||:|:|||.||.:|...|.||:::||.||.::|
Mouse    38 SRMQKNYWRTKQVFIKATGKKEDEHVVASDAELDAKLEVFHSIQETCNELVKIVEKYQLRLNVIS 102

  Fly    69 QEECVFGRFLKEAGKRSRTTGGSIAHTA-KAVSFAGQQRMCVRVPLLRLQHEVDVFRCRAIKDTE 132
            :||...|.|||...:|..|..|.:...| ||:..:.:||:.:..||.||:.||..|..|||.||.
Mouse   103 EEENELGLFLKFQAERDSTQAGEMMDAAGKALCSSAKQRLALCTPLSRLKQEVATFSQRAISDTL 167

  Fly   133 QTLQTMEKERTEYRAALSWMKSASQELDPDTGKGLDKFRTAQAHVRVAKHNFDGYSMDSIQKIDL 197
            .|:..||:.|||||.||.|||.|||||||||.|.::|||..|..||.:|.:||....|..||:||
Mouse   168 VTINRMERARTEYRGALLWMKDASQELDPDTFKQMEKFRKVQNQVRNSKDSFDKLKKDVCQKVDL 232

  Fly   198 LAAARCNMYSHALVAYVTELKNFAQKAASTFQTISKALIIKPKYDFCVLKELSQ---------NE 253
            |.|:||||.||:|..|...|..|.:|.|.....|.:|......|||..||.|..         .|
Mouse   233 LGASRCNMLSHSLTTYQRTLLGFWEKTAQMMTQIQEACAGFHPYDFLALKRLQDTPGNLTADCTE 297

  Fly   254 GSTEEVPPIEAVDKDQSLFFANEYQDKLETQPEI-----KESEEDKPSAPPNACGDN-------- 305
            |.||  ......|.::......|.:::.|.:|.:     ::|.|          ||:
Mouse   298 GQTE--GSCLTTDLNKVALSEEEEEERFEREPAVARALPRDSLE----------GDDFEKEFSFL 350

  Fly   306 ESLLIELSKQLEDSPLIDAPLDEDIPAQNSTNKLWSRLFSQQ----------NQQPIPSQVATDS 360
            .|||         ||...:..:.....|.:.....:.|.||:          :.|.:|||: .|.
Mouse   351 NSLL---------SPTSSSASEFTQECQPACGSPCTGLTSQEPSVGPGSLTSSSQFLPSQL-FDL 405

  Fly   361 KASAGGATPVPSKSQTTNNPWLDLFADLDPLANPQA 396
            ...|.||...|:......:.|.:|||||.||:||.|
Mouse   406 GLHADGAFNTPNNGNQDMSAWFNLFADLGPLSNPDA 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ICA69	NP_001246855.1	BAR_ICA69	33..235	CDD:153345	98/202 (49%)
		ICA69	<345..396	CDD:282483	21/60 (35%)
Ica1l	XP_036009489.1	BAR	67..269	CDD:416402	98/201 (49%)
		ICA69	276..452	CDD:398355	47/188 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849683
Domainoid	1	1.000	220	1.000	Domainoid score	I2605
eggNOG	1	0.900	-	-		E1_KOG3891
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16323
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3259
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003439
OrthoInspector	1	1.000	-	-		otm43576
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10164
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2749
SonicParanoid	1	1.000	-	-		X2807
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.880