Protein Alignment ICA69 and ical1

DIOPT Version :10

• Sequence 1: NP_649283.1
• Gene: ICA69 / 40331
• FlyBaseID: FBgn0037050
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_009300497.1
• Gene: ical1 / 378720
• ZFINID: ZDB-GENE-030910-4
• Length: 586
• Species: Danio rerio
• Alignment Length: 568
• Identity: 170/568 - (29%)
• Similarity: 237/568 - (41%)
• Gaps: 172/568 - (30%)

  Fly     4 SEVQHQFWITKKVVQRKLGTKEDKHIISSDAELDSKIEVFKSISDTSLNLCKIIDQYQERLCILS 68
            :.:|.:||.||:|:.:..|.|||:|:::|||:||:|:|.|:|:..|...|.|:|::||:|:..||
Zfish    25 ARMQKKFWKTKQVLIKATGKKEDEHVVASDADLDAKLEFFRSVQSTCTELLKVIEKYQQRITHLS 89

  Fly    69 QEECVFGRFLKEAGKRSRTTGGSIAH-TAKAVSFAGQQRMCVRVPLLRLQHEVDVFRCRAIKDTE 132
            |||...|.||:...:..:|..||:.. |:||:..:.:||:.:..||.||:.||:.||.|||.|:.
Zfish    90 QEENELGLFLRFQAEHDKTKAGSMMDATSKALCCSAKQRLALCTPLHRLEQEVETFRRRAIADSL 154

  Fly   133 QTLQTMEKERTEYRAALSWMKSASQELDPDTGKGLDKFRTAQAHVRVAKHNFDGYSMDSIQKIDL 197
            .|:..|||.||||||||.|||::||||||||.|.|:|||..||.||..|..||....|..||:|:
Zfish   155 LTVSRMEKARTEYRAALLWMKASSQELDPDTYKQLEKFRMVQAQVRETKVCFDKLKNDVCQKVDM 219

  Fly   198 LAAARCNMYSHALVAYVTELKNFAQKAASTFQTISKALIIKPKYDFCVLKEL------------- 249
            |.|:||||.||:|..|.|.|..:.:|.|.....|.:|......|.|..||||
Zfish   220 LGASRCNMLSHSLCTYQTTLLQYWEKTAHVMSGIHEAFKGYVPYQFTTLKELRDPLDQIASTQPE 284

  Fly   250 -----------------------------------------------------SQNEGS------ 255
                                                                 .|:.||
Zfish   285 EDKKDEEKKNHLDKSSHSSREASLKALVTDLLVSLEDEQLGESSDTVSTLAVDGQSRGSDSSLCA 349

  Fly   256 ------TEEVPPIEAVDKDQSLFFANEYQDKLET------------QPEIKESEEDKPSAPPNAC 302
                  .|::.||.....|..|.......|.:.:            ||:|..    :.|.||...
Zfish   350 SLDSALIEQLGPIGGSTTDDDLLLMTPELDSIRSLTPALHSSMSIMQPQILR----EASTPPATQ 410

  Fly   303 GDNESLLIELSKQLEDSPLI-----------------DAPLDEDIPAQNST------NKLWSRLF 344
            .|..:|...|..|:....|:                 |....:|:.:..:.      :|.|...|
Zfish   411 WDTGALSCSLQPQIAGRDLLSETFHSAEGKEEEGERGDLAFLQDLLSPGAAGGTSEFSKAWQDAF 475

  Fly   345 SQQNQQP-------------------IPSQVATDSKASAGGATPVPSKSQ--------------- 375
            ......|                   :|||:...|.::.|.|||...::|
Zfish   476 GCFEAPPAPVTAALSQTETTNIPSGFLPSQLLDHSLSATGWATPPMFQAQPLQPPSTGGQSQPTL 540

  Fly   376 TTNNP--------------WLDLFADLDPLANPQAFDLKLSGGRSVAE 409
            .|.||              |.:||||||||:||.|.      |||..|
Zfish   541 NTTNPSANAPKGSSRDMSAWFNLFADLDPLSNPDAI------GRSDQE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ICA69	NP_649283.1	BAR_ICA69	33..235	CDD:153345	97/202 (48%)
		ICA69	<345..396	CDD:461374	24/98 (24%)
ical1	XP_009300497.1	BAR_ICA69	54..257	CDD:153345	97/202 (48%)
		ICA69	262..586	CDD:461374	60/331 (18%)