Protein Alignment ICA69 and Ica1l

DIOPT Version :10

• Sequence 1: NP_649283.1
• Gene: ICA69 / 40331
• FlyBaseID: FBgn0037050
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_006245056.1
• Gene: Ica1l / 316432
• RGDID: 735110
• Length: 490
• Species: Rattus norvegicus
• Alignment Length: 461
• Identity: 166/461 - (36%)
• Similarity: 227/461 - (49%)
• Gaps: 88/461 - (19%)

  Fly     4 SEVQHQFWITKKVVQRKLGTKEDKHIISSDAELDSKIEVFKSISDTSLNLCKIIDQYQERLCILS 68
            |.:|.::|.||:|..:..|.|||:|:::||||||:|:|||.||.:|...|.|.:::||.||.::|
  Rat    39 SRMQKKYWKTKQVFIKATGKKEDEHVVASDAELDAKLEVFHSIQETCNELVKAVEKYQLRLNVIS 103

  Fly    69 QEECVFGRFLKEAGKRSRTTGGSIAHTA-KAVSFAGQQRMCVRVPLLRLQHEVDVFRCRAIKDTE 132
            :||...|.||....:|..|..|.:...| ||:..:.:||:.:..||.||:.||..|..|||.||.
  Rat   104 EEENELGLFLTFQAERDATQAGKMMGAAGKALCSSAKQRLALCTPLSRLKQEVATFSQRAISDTS 168

  Fly   133 QTLQTMEKERTEYRAALSWMKSASQELDPDTGKGLDKFRTAQAHVRVAKHNFDGYSMDSIQKIDL 197
            .|:..||:.|||||.||.|||.|||||||||.|.::|||..|..||.:|..||...||..||:||
  Rat   169 VTINRMERARTEYRGALLWMKDASQELDPDTFKQVEKFRKVQIQVRNSKDCFDKLKMDVCQKVDL 233

  Fly   198 LAAARCNMYSHALVAYVTELKNFAQKAASTFQTISKALIIKPKYDFCVLKELSQNEGSTEEVPPI 262
            |.|:||||.||:|..|...|..|.:|.|.....|.:|......|||..||:|....|:      :
  Rat   234 LGASRCNMLSHSLATYQRTLLGFWEKTAQMMSQIQEACAGFHPYDFMALKQLQDTPGN------L 292

  Fly   263 EAVDKDQ----SLFFAN-------EYQDKLETQPEI---------------KE------------ 289
            .|.||::    |....|       |.:::.|.:|.:               ||
  Rat   293 TAEDKEEQTEGSCLSTNLNKVALSEEEERFEREPAVARALPRDSLEGDDFEKEFSFLSSLLSPTS 357

  Fly   290 ------SEEDKPSAPPNACGDNESLL----------IELSKQLEDSPLIDAPLDEDIPAQNSTNK 338
                  ::|.:|     ||| :.||:          :..|.|...|.|.|..|..| .|.||
  Rat   358 SRASECTQECQP-----ACG-SPSLMCQEPSLGPGPLTSSSQFLPSRLFDLGLHAD-GAFNS--- 412

  Fly   339 LWSRLFSQQNQQ-----PIPSQVATDSK--------ASAGGATPVPSKSQTTNNPWLDLFADLDP 390
             |:   ||:..:     |:|||.....|        ||...:...|:......:.|.:|||||.|
  Rat   413 -WA---SQEGSEHSDTLPVPSQHPKKLKWPPHAGYPASYTLSLDAPNSGNQDMSAWFNLFADLGP 473

  Fly   391 LANPQA 396
            |:||.|
  Rat   474 LSNPDA 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ICA69	NP_649283.1	BAR_ICA69	33..235	CDD:153345	97/202 (48%)
		ICA69	<345..396	CDD:461374	20/63 (32%)
Ica1l	XP_006245056.1	ICA69	276..490	CDD:461374	56/224 (25%)
		BAR	68..270	CDD:472257	97/201 (48%)