Protein Alignment siz and CYTH2

DIOPT Version :9

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_006723535.1
• Gene: CYTH2 / 9266
• HGNCID: 9502
• Length: 421
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 116/419 - (27%)
• Similarity: 195/419 - (46%)
• Gaps: 98/419 - (23%)

  Fly   737 EQQQHEQQQLQAAAAAAGVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGV 801
            |.|:..::..:|.:...|:..|.......|.|:..:|...||..|:|||.:|:....|:|||:.:
Human    54 EIQRLREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEI 118

  Fly   802 ARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKI 866
            ||||...:||::..||:|||. :.:.|:|||..|....:.:...:..|||:|...||:|||||||
Human   119 ARFLYKGEGLNKTAIGDYLGE-REELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKI 182

  Fly   867 ERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGI 931
            :|:||.|:||||.||.   |..:|:||.:||:||:|||||.||.||::.  :..:|.|:...|||
Human   183 DRMMEAFAQRYCLCNP---GVFQSTDTCYVLSFAVIMLNTSLHNPNVRD--KPGLERFVAMNRGI 242

  Fly   932 DDCHDIDKDMLMGIYDRVKSDEFK----PGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLY 992
            ::..|:.:::|..:||.::::.||    .|:|                    |.|        .:
Human   243 NEGGDLPEELLRNLYDSIRNEPFKIPEDDGND--------------------LTH--------TF 279

  Fly   993 EIPDVNKKERPGVHQREVFLFNDLLVITKIFSKKKT----------SVTYTF--------RNSFP 1039
            ..||           ||.:|.       |:..:.||          :..|.|        |...|
Human   280 FNPD-----------REGWLL-------KLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIP 326

  Fly  1040 LCGTVVTLLDMPNYPFCIQL-------------SQKVDGKI------LITFNARNEHDRCKFAED 1085
            |....:..:|.|..|.|.:|             ..:.||::      :...:|..:.::.::.:.
Human   327 LENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKS 391

  Fly  1086 LKESIS-----EMDEMESLRIEAELERQK 1109
            ::.::|     ||......||..:.::::
Human   392 IQAAVSVDPFYEMLAARKKRISVKKKQEQ 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:279680	79/187 (42%)
		PH_IQSEC	981..1108	CDD:270128	27/168 (16%)
CYTH2	XP_006723535.1	Sec7	83..265	CDD:396096	79/187 (42%)
		PH_GRP1-like	280..399	CDD:269954	22/136 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148850
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740