Protein Alignment siz and GEA2

DIOPT Version :9

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_010892.1
• Gene: GEA2 / 856691
• SGDID: S000000748
• Length: 1459
• Species: Saccharomyces cerevisiae
• Alignment Length: 455
• Identity: 116/455 - (25%)
• Similarity: 187/455 - (41%)
• Gaps: 138/455 - (30%)

  Fly   708 AAATAAGGMPP---------ADDHAISSHTSAAQYEQHEQQQHEQQQLQAAAAAAGVAQNYKMSE 763
            :|.|....:||         .||  :..|......|:..:|::|.:.|:               :
Yeast   509 SALTTTESVPPICLEGLVSLVDD--MFDHMKDIDREEFGRQKNEMEILK---------------K 556

  Fly   764 TIRKRQYRVGLNLFNKKPEKGITYLIRRGFL-ENTPQGVARFLITRKG-LSRQMIGEYLGNLQNQ 826
            ..||.::....|.||:||:|||..||.:||: .::.:.:|.||..... ::::.||..|.:..
Yeast   557 RDRKTEFIECTNAFNEKPKKGIPMLIEKGFIASDSDKDIAEFLFNNNNRMNKKTIGLLLCHPD-- 619

  Fly   827 FNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCE------------ 879
             .:::|:.:....|.||.:||.|:|.....||:|||:|:|||::|.||..|||
Yeast   620 -KVSLLNEYIRLFDFSGLRVDEAIRILLTKFRLPGESQQIERIIEAFSSAYCENQDYDPSKISDN 683

  Fly   880 CNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMG 944
            ...||......:|::|:|:::|||||||||.|.:|  ..|..||:..||:|.  |:  .||....
Yeast   684 AEDDISTVQPDADSVFILSYSIIMLNTDLHNPQVK--EHMSFEDYSGNLKGC--CN--HKDFPFW 742

  Fly   945 IYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLYEIPDVNKKERPGVHQRE 1009
            ..||:                                      ||.:.:...|..:|..|..:..
Yeast   743 YLDRI--------------------------------------YCSIRDKEIVMPEEHHGNEKWF 769

  Fly  1010 VFLFNDLL----VITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNYPFCIQLSQKVDGKILIT 1070
            ...:|:|:    |||:|  ||.|....          ..:|.|::.|:...|  .::|...|:.|
Yeast   770 EDAWNNLISSTTVITEI--KKDTQSVM----------DKLTPLELLNFDRAI--FKQVGPSIVST 820

  Fly  1071 -FN----ARNEH---------DRCKFA----------EDLKESI---------SEMDEMESLRIE 1102
             ||    |.::|         |:|.:.          .|:..||         |..||:.:|..|
Yeast   821 LFNIYVVASDDHISTRMITSLDKCSYISAFFDFKDLFNDILNSIAKGTTLINSSHDDELSTLAFE 885

  Fly  1103  1102
            Yeast   886  885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:279680	70/201 (35%)
		PH_IQSEC	981..1108	CDD:270128	35/159 (22%)
GEA2	NP_010892.1	COG5307	298..1331	CDD:227623	116/455 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344266
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10663
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840