Protein Alignment siz and GEA1

DIOPT Version :9

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_012565.1
• Gene: GEA1 / 853488
• SGDID: S000003792
• Length: 1408
• Species: Saccharomyces cerevisiae
• Alignment Length: 471
• Identity: 116/471 - (24%)
• Similarity: 193/471 - (40%)
• Gaps: 124/471 - (26%)

  Fly   708 AAATAAGGMPPADDHAISSHTSAAQYEQHEQQQHEQQQLQAAAAAAGVAQNYK----MSETIRKR 768
            ||...:..:||.   .:....|..:...::.|:.::         |...:|.|    :.:..||.
Yeast   491 AAVNTSNNIPPI---CLEGVLSLIENIYNDLQRFDR---------AEFVKNQKEIDILKQRDRKT 543

  Fly   769 QYRVGLNLFNKKPEKGITYLIRRGFLE-NTPQGVARFLITRKG-LSRQMIGEYLGNLQNQFNMAV 831
            ::.:.:..||:|.:|||..||.:||:: ::.:.:|.||....| |:::.||..|.:.:   ..::
Yeast   544 EFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPK---KTSL 605

  Fly   832 LSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNA-------------- 882
            |..|....|..|.:||.|:|.....||:|||:|:|||::|.||.:|....:
Yeast   606 LKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKN 670

  Fly   883 --------DIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDK 939
                    ||:.....:|::|||:::|||||||.|.|.:|.  .|..:|:..||||..:..|..:
Yeast   671 GSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKD--HMTFDDYSNNLRGCYNGKDFPR 733

  Fly   940 DMLMGIYDRVKSDEFKPGSDH----------------VTQVM-KVQATIVGKKPNLALPHRRLVC 987
            ..|..||..:|..|.....:|                .|.|| ::|
Yeast   734 WYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQ------------------- 779

  Fly   988 YCRLYEIPDVNKKERPGVHQREVFLFN---DLLVIT--KIFS---------------KKKTSVTY 1032
              |.:..| ::|..:..:.|.|..:|:   |:::.|  |||:               .|.|.:.|
Yeast   780 --RDFTNP-ISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINY 841

  Fly  1033 TFRNSFPLCGTVVTLLDMPNYPFCIQLSQK-----VDGKILITFNARNEHDRCKFAEDLKESISE 1092
            .|........||:.|.:|..   ..|.|.|     ||...|:..          |.||....||.
Yeast   842 YFSFDQSYNDTVLHLGEMTT---LAQSSAKAVELDVDSIPLVEI----------FVEDTGSKISV 893

  Fly  1093 MDEMESLRIEAELERQ 1108
            .:  :|:|:....:.|
Yeast   894 SN--QSIRLGQNFKAQ 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:279680	68/211 (32%)
		PH_IQSEC	981..1108	CDD:270128	32/151 (21%)
GEA1	NP_012565.1	COG5307	283..1325	CDD:227623	116/471 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344265
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10663
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840