Protein Alignment siz and psd3l

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_068079995.1
• Gene: psd3l / 559329
• ZFINID: ZDB-GENE-030131-8195
• Length: 1135
• Species: Danio rerio
• Alignment Length: 1050
• Identity: 200/1050 - (19%)
• Similarity: 358/1050 - (34%)
• Gaps: 323/1050 - (30%)

  Fly   335 RARNAAVTIQRAFRHYMMVKKFASITAMAKAEKRLSRRMVVTASSLGLAEEGASS---------- 389
            |.|.|......||.........|.|.|.||.|           ...|.||:.:||
Zfish   165 RLRPAVPVKVEAFDRVSSSSTHAEIVAKAKYE-----------FLFGKAEDSSSSDSVTSPPQAK 218

  Fly   390 ---SSAYGSATE---------------------SQLTEQQQQQQAQQQQQPRVTIMAGPAGAASP 430
               ||...|..:                     |.||.:.|....:|..      ::|.| .|||
Zfish   219 EKGSSILDSTLDDDDIDETSLFQEIDRELSNLLSGLTARSQHAATEQGS------LSGDA-TASP 276

  Fly   431 -----GLSRTPPTRSLSMRERRQLDCSPIPRSQSGASPASISSSTVSTSALASHPHVNLLHAAEP 490
                 |.::|.|:: |.| ..:.||.      |:|.|  .::..::.||.|........| ..:|
Zfish   277 MIPCNGQNQTLPSQ-LEM-ANQGLDL------QNGQS--ELTGDSLLTSGLLFDSWCEAL-IKDP 330

  Fly   491 HYYNAQALPQGAAYYTSYHGSPHDLSYAS--SADTSLNASWVNTSGHSPHTPYYSAAQIYMRPKG 553
                           :|...:.::||..|  :|...|:||         .||    |..::.|.|
Zfish   331 ---------------SSVMAAANELSCFSTGNAPDKLDAS---------PTP----AGAHVEPSG 367

  Fly   554 GSTTPTPSCSGSTGSGSGGSGSGSSKKVPPEVPKRTSSITAQQQTQLLLLQ-------------R 605
            ...:     ..::|..:.|..:||...:..:.|.......:.:::..:|.:             .
Zfish   368 EVLS-----QENSGKETEGKRTGSPSPIRTDEPSAEIVDESLEESNKILAEVPGIFSGFLEGGKL 427

  Fly   606 QTPPPPSLLRTNGLCKTAENGSLTSVQSSGSDSSVTSAERNLNSDLGSDRSNSPHTWKRGTALNS 670
            :..||..|.......::..||.:    .:||..| .|.:..:..|:   :|.:.....:|:.|..
Zfish   428 RDKPPKKLRFVESRAESLVNGEM----QNGSHQS-CSVKEEVTQDI---QSTAAAGVPQGSVLRP 484

  Fly   671 SQQFSTHSAD--SAGAVSGGGVGVAGGAGVYAAQMQAAVAAATAAGGMPPADD------HAISSH 727
            .|:.:.:..|  |||..:.|.:..   ..|::.|.:..:.:....|.:..:.|      :.:...
Zfish   485 EQKPTENGTDRCSAGKSAAGEIDT---TDVFSCQFENILESERLRGTLYSSMDSLDALSNPVPEP 546

  Fly   728 TSAAQYEQH----------EQQQHEQQQLQAAAAAAGVAQNYK-MSETIRKRQYRVGL------- 774
            |..:..|..          .||:.:.:.|....||..::.:.: :|.|..|.:.:..|
Zfish   547 TPQSTLEPSFAFDIPLTPMIQQRLKDRSLFLEPAAPDLSSDTEVLSVTSTKERGKTALEVTSSFL 611

  Fly   775 ------------NLFNKKPEK-----------GI-------------------TYLIRRGFLENT 797
                        |..|::..|           |:                   |.::..|  ..:
Zfish   612 SAGCKDSCAALANGLNERDPKDWLQGCLSSDAGLKDVLSDWDSDMDVVECLKDTDVLHNG--SRS 674

  Fly   798 PQGVARFLITR----KGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFR 858
            .|..||.|..|    :|..|..:.::||. .|.|:..|...:....:.:.:.:|.:||.|...|.
Zfish   675 DQEAARRLARRLYHLEGFRRSDVAKHLGK-NNDFSKMVAEEYLTFFEFTDQTLDQSLRCFLKAFS 738

  Fly   859 MPGEAQKIERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVED 923
            :.||.|:.||::..||.||.:||..|:   .:.|.:..|..|:::||||||.||:  .::|..::
Zfish   739 LMGETQERERVLIHFSNRYYQCNPTII---TAQDGVHCLTCALMLLNTDLHGPNI--GKKMTCQE 798

  Fly   924 FIKNLRGIDDCHDIDKDMLMGIYDRVKS---------DEFKPG------SDHVTQVMKVQATIVG 973
            ||.||.|::...|..:::|..:|:.:|:         ||.|..      .:|.:....:.....|
Zfish   799 FINNLDGLNGGQDFPRELLKSLYNSIKNEKLEWAVDGDELKKSLSELADKNHHSHSKSISRISSG 863

  Fly   974 KKPNLALPH---------------------------------------RRLVCYCRLYE------ 993
            ..|.|.:.|                                       :.::.|.:..|
Zfish   864 SNPFLDIAHDPNAAVYKTGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGMILYLQKDEYKPEKA 928

  Fly   994 IPDVNKKERPGVHQREVFLFNDLLVITKIFSKKKTSV---------TYTFRNSFP--------LC 1041
            :.:.:.|....||.        .|.|..:..:||.:|         .:.|:...|        :.
Zfish   929 LSEDDLKNAISVHH--------ALAIKAMDYEKKPNVLKLKTADWRVFLFQAQSPEEMESWIRII 985

  Fly  1042 GTVVTLLDMPNYPFCIQLSQKVDGKILI--------------TFNARNEHDRCKFAE------DL 1086
            .:|..:...|::|..|. |||...:.|:              :..|:.:|...:.||      |.
Zfish   986 NSVAAMFSAPSFPAAIG-SQKKFSRPLLPATTTRMSQEEQLKSHEAKLKHVSTELAEHRSYPPDK 1049

  Fly  1087 KESISEMD---------EMESLRIEAELERQKSARNRAPGNAENRDSGVADVEVCPCPYQQGSQA 1142
            |....|:|         |.|..|.|..::..|....... .|::.|:.:...:..|...|....|
Zfish  1050 KVKAKEIDEYRLKEHYLEFEENRYEMYVKLLKEGVKELL-TAKDGDAALKKSQSSPSLNQDSQPA 1113

  Fly  1143 SGEQAPNSAD 1152
            :.:...|:::
Zfish  1114 AAKVKRNTSE 1123

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	59/249 (24%)
		PH_IQSEC	981..1108	CDD:270128	33/217 (15%)
psd3l	XP_068079995.1	Sec7	675..829	CDD:238100	50/159 (31%)
		PH_EFA6	873..998	CDD:270107	14/132 (11%)