Protein Alignment siz and step

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001036375.2
• Gene: step / 35425
• FlyBaseID: FBgn0086779
• Length: 727
• Species: Drosophila melanogaster
• Alignment Length: 795
• Identity: 184/795 - (23%)
• Similarity: 306/795 - (38%)
• Gaps: 210/795 - (26%)

  Fly   444 RERRQLDCSP-------IPRSQSGASPASISSSTVSTSALASHPHVNLLHAAEPHYYNAQALPQG 501
            |:.:...|||       :.|.|    |...|...:||:.:.....|:|      .::.::: |:.
  Fly    20 RQPKNKKCSPGLGGSESVGRKQ----PLQRSCLDLSTTRVGCDGCVSL------EFFQSES-PES 73

  Fly   502 AAYYTSYHGSPHDLSYASSADTSLNASWVNTSGHSPHTPYYSAAQIYMRPKGGSTTPTP-----S 561
            ....::::.:..::|.|...|                    :...:..|..|..::|:.     |
  Fly    74 RRSNSTFYVNTQNVSSAVFKD--------------------NRQPLLERGSGSDSSPSSVCVRCS 118

  Fly   562 CSGSTGSGSGG-----SGSGSSKKV---PPEVPKRTS--SITAQQQTQLLLLQRQTPPP--PSLL 614
            |:..|.||...     :...|..|:   ||..|:..|  ..|:.....:..|...:|||  |:|
  Fly   119 CNSITKSGDRNETPTMATPKSDIKIALKPPPKPRSPSMAPYTSVATYNITKLAPDSPPPASPTL- 182

  Fly   615 RTNGLCKTAENGSLTSVQSSGSDSSVTSAER----NLNSDLGSDRSNSPHTWKRGTA-------- 667
                        |..:|..|...:.||..:|    ..|::|.|.|:...||....|.
  Fly   183 ------------STQTVNCSDVTTKVTEVQRLPCDEPNTELISKRTEYKHTTITTTTRTLIVSRP 235

  Fly   668 ----LNSSQQFSTHSA--DSAGAVSGGGVGVAGGAGVYAAQMQAAVAAATAAGGMPPADDHAISS 726
                ||.:.:.....:  .|.....|..:.|....|.....|:|...:..:....|..||.....
  Fly   236 VELLLNENGEIIARRSPRKSRSNSLGRMLDVQNEIGTGGLFMEADPCSKNSLPPPPYIDDMRFID 300

  Fly   727 HTSAAQYE------------------QHEQQQHEQQQLQAAAAAAGVAQNY-------------- 759
            .:|.:|.|                  .::.::..||.....:....:.:||
  Fly   301 DSSNSQSESERNSNIHKTNKYTSKNNNNDSKRESQQSNLCESCRMLLDRNYINTEQSDNLVILRR 365

  Fly   760 -------KMSETI----------------RKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGV 801
                   ::.|.:                :.:|..:|...||..|:|||.||:....|.:.||.|
  Fly   366 PSKQIKDELCEVVSEMEALDVPEDCKHSNKDKQMSIGRKKFNMDPKKGIEYLVENRLLRHDPQDV 430

  Fly   802 ARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKI 866
            |.||...:||::..||:|||. :|.||..||..|....|.:...:..|||:|...||:|||||||
  Fly   431 AHFLYKGEGLNKTAIGDYLGE-KNDFNEDVLKAFVALHDFTNLILVQALRQFLWSFRLPGEAQKI 494

  Fly   867 ERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGI 931
            :|:||.|:||||:.|.||   ..::||.:||:||||||||.||.|::|.  :..|:.||...|||
  Fly   495 DRMMETFAQRYCQLNPDI---FTNTDTCYVLSFAIIMLNTSLHNPSVKD--KPTVDQFISMNRGI 554

  Fly   932 DDCHDIDKDMLMGIYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLYEIPD 996
            ::..|:.:.:|..:|:.::::.||...|....:|                        ..:..||
  Fly   555 NNGGDLPRGLLESLYESIRTEPFKIPQDDGNDLM------------------------HTFFNPD 595

  Fly   997 VNKKE--------RPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNY 1053
               ||        |....:|..|:.||..:....::..|..     |...||....|..:...:.
  Fly   596 ---KEGWLWKQGGRYKSWKRRWFILNDNCLYYFEYTTDKEP-----RGIIPLENISVREIHDRSK 652

  Fly  1054 PFCIQL-----------------SQKVDGK-ILITFNARNEHDRCKFAEDLKESISEMDEMESLR 1100
            |.|.:|                 .:.|:|| .:...:|..|.|:.::.:.|.:|||.....:.|
  Fly   653 PHCFELFATGGADIIKACKTDSEGKVVEGKHTVYRMSAATEEDQQEWIKRLTQSISHNPFYDIL- 716

  Fly  1101 IEAELERQKSARNRA 1115
                ::|:|.|.:::
  Fly   717 ----VQRKKKALSKS 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	80/187 (43%)
		PH_IQSEC	981..1108	CDD:270128	28/152 (18%)
step	NP_001036375.2	Sec7	395..577	CDD:460178	80/187 (43%)
		PH_GRP1-like	592..710	CDD:269954	27/125 (22%)