Protein Alignment siz and sec73

DIOPT Version :9

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001342851.1
• Gene: sec73 / 3361502
• PomBaseID: SPAC19A8.01c
• Length: 1082
• Species: Schizosaccharomyces pombe
• Alignment Length: 637
• Identity: 134/637 - (21%)
• Similarity: 236/637 - (37%)
• Gaps: 148/637 - (23%)

  Fly   520 SADTSLNASWVNTSGHSPHTPYYS-----AAQIYMRPKGGSTTPTPSCSGSTGSGSGG-----SG 574
            |:..|.|.|..:|:.:||:...:|     ::|.|:..:........|...|:||.:..     |.
pombe     7 SSQESSNKSEKDTTVNSPNASSFSSFFKKSSQTYLSKRSEKLNEHNSKLKSSGSFTSNSQTDLSN 71

  Fly   575 SGSSKK--VPPEVPKRTSSITAQQQTQLLLLQRQTP----PPPSLLRTNGLCKTAENGSLTSVQS 633
            |.||||  :...:.:...|..........|.|..:|    ...|:...:...|...:...|.:..
pombe    72 SPSSKKKNIFYPIARAKHSFYFNHNWSSDLQQANSPVASYSSQSVSNDSNFPKDVTSPISTDLSG 136

  Fly   634 SG----SDSSVTSAE---------------RNLNSDLGSDRSNSPHTW---KRGTALNSSQQFST 676
            |.    |.||:.||:               ::.|.|:.|..|:.....   |.|..||  ||...
pombe   137 SNPSLKSPSSINSAKLRASRSFFRFPKWSRKSWNPDVNSTTSSPSEVGSLDKAGGPLN--QQNEN 199

  Fly   677 HSADSAGAVSGGGVGVAGGAGVYAAQMQAAVAAATAAGGMP----PADDHAISSHTSAAQYEQHE 737
            .||:|...:...|   ...:.|..:.:...:|:      :|    |....:|||     .|.:..
pombe   200 LSAESDNTILQNG---TRKSSVKMSDLGKRIAS------LPVVKRPPIQFSISS-----DYIKPV 250

  Fly   738 QQQHEQQQLQAAAAAAGVAQNYK--------------------MSETI-------RKRQYRVGLN 775
            .:..:...:.:.:::.|..:.|:                    .|.||       |.|:.|..:.
pombe   251 DKSDQTSNVPSPSSSVGSLRLYRSPSIPNDVEQPQPQSSRSRPRSSTIPTQRTLERLRENRSSIF 315

  Fly   776 LF---NKKPEKGITYLIRRGFL-ENTPQGVARFLITRKGLSRQMIGE-YLGNLQN---------- 825
            .|   .:..::.:...|....| .:......:||.:...|:.....| ||..|:.
pombe   316 SFRTLRRDDDECVAQTIENSALFSDIKPNPTKFLSSVPELTADDTAESYLSKLRETVPYSRMIPV 380

  Fly   826 -------QFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNAD 883
                   ..|.|:..|.: .::...|.:|..||.|.....:|.|.|:|:|::..||:||.|||.
pombe   381 LAEKDHVTLNKALHLCMS-GMEFENRPLDFCLRLFLLKSHLPKETQQIDRVINAFSKRYFECNP- 443

  Fly   884 IVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMGIYDR 948
              |...|.|..::|.|:::||:||:...|.|  .:|..::|| ||..||   ::..:::...||.
pombe   444 --GMFSSQDQCYILVFSLMMLHTDVFNSNNK--HKMTKQEFI-NLCDID---ELAPEIMEYYYDN 500

  Fly   949 VKSDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLYEIPDVNKKERPGVHQREVFLF 1013
            :....|....|        :..::.|:.|               |..:...::|.|:......|.
pombe   501 ITFTPFVNLDD--------ELLLIEKEKN---------------EKYNFTSRKRLGLSPYTFTLE 542

  Fly  1014 NDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLD---MPNYPFCIQLSQK 1062
            |.|.:     |:.:.|::|..:...|....:.:||:   :.:.|..|||..|
pombe   543 NQLNI-----SRPEISLSYDGKFISPGIKDIASLLNVRKLISSPAIIQLVSK 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:279680	53/209 (25%)
		PH_IQSEC	981..1108	CDD:270128	17/85 (20%)
sec73	NP_001342851.1	COG3942	5..>222	CDD:332523	48/219 (22%)
		Sec7	<381..506	CDD:307500	40/134 (30%)
		PH	<710..767	CDD:214574

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10663
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000