Protein Alignment siz and CG5937

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_572289.2
• Gene: CG5937 / 31537
• FlyBaseID: FBgn0029834
• Length: 2051
• Species: Drosophila melanogaster
• Alignment Length: 634
• Identity: 118/634 - (18%)
• Similarity: 180/634 - (28%)
• Gaps: 253/634 - (39%)

  Fly   655 RSNSPHTWKRGTALNSSQQFSTHSADSAGAVSGGGVGVAGGAGVY-------------------- 699
            :..||.....|.........|:.||......:||||| .||:.:.
  Fly  1492 QQQSPSVQDHGCGYTQQYDSSSSSASEEQQKNGGGVG-GGGSNLIESPTKISGSATLALKQLLLV 1555

  Fly   700 ----AAQMQAAVAAATAAGGMPPADDHAISS-----------------HTSAA---------QYE 734
                |||.|.|:|..:.:     ...|.|.|                 |.:..         .:.
  Fly  1556 LIECAAQSQEAIARISVS-----CLKHVILSTGMLFNESQWMIACSAIHRACTVTIAPLRQLSFA 1615

  Fly   735 QHEQQQ-------------HEQQQLQAAAAAAGVAQNYKMSETIRKRQYRVGLN----------- 775
            .||:..             .....|:..|....:||...:|:    .|...|.|
  Fly  1616 FHEKSNSFYGDCANVKVAARRDSSLEELARIYALAQQVFLSD----NQREPGQNQAPTPSASQCK 1676

  Fly   776 LFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQMIGEYLGNLQNQFNM----------- 829
            |.:.:....:.|.:..||..|....|.|  |..|.|       .:|.|.||..:
  Fly  1677 LSDDRSYSFLLYPLNNGFNSNLDNFVIR--IPFKNL-------VVGLLANQMLLQLVAKLLLSRL 1732

  Fly   830 -----AVLSCF-----------AMELDLSGRQVDVALRKFQAYF-------RMPGEAQKIERLME 871
                 ||.:|.           :.:.||..|..::.||..:.|.       ..||    ::.||:
  Fly  1733 KCVPQAVSTCIFDNYAASAASPSHDYDLDFRSKEILLRCVKQYLMSALEFDSRPG----LKFLMQ 1793

  Fly   872 IFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHD 936
            ..|.  .|..|::..::.||..|:.:|.....|| |:...||.||..    :||     ::.|
  Fly  1794 KVSN--IEYAANLYKQMTSSWMIYYIALVDSHLN-DIVVYNLGPEDL----NFI-----LESC-- 1844

  Fly   937 IDKDMLMGIYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVC-------YCRLYEI 994
                                        .::..|.|.||.|..   |.|.|       .|.||
  Fly  1845 ----------------------------SRLNTTTVKKKENFV---RYLFCLQDAWNLVCELY-- 1876

  Fly   995 PDVNKKERPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMP-NYPFCIQ 1058
                 .....:|:.|                   |.:...|...|      .||..| ..|.||.
  Fly  1877 -----LSNSALHEIE-------------------SGSGKLRQKPP------QLLHHPQTKPMCIS 1911

  Fly  1059 LSQKVDGKILIT-----FNARNEHDRCKFAEDLKESISEMDEMESLRIEAEL-ERQKSARNRAPG 1117
            |:...|.::..|     ..:.....:|          .::.|.|::.:...: |.|...|:.
  Fly  1912 LNGNGDAEMTDTGSGSGSGSSTSPSKC----------VQLQEEENVTMTTLISEFQPKCRSN--- 1963

  Fly  1118 NAENRDSGVADVEVCPCPYQQGSQASGEQAPN-SADNSQQLKRSALSNS 1165
                             |:....||...:|.: |.:..||...|.|.:|
  Fly  1964 -----------------PFDTNRQAKSSEAESISPEIEQQRASSILKDS 1995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	47/232 (20%)
		PH_IQSEC	981..1108	CDD:270128	24/140 (17%)
CG5937	NP_572289.2	Sec7	451..692	CDD:469626
		DUF1981	1115..>1177	CDD:462756