Protein Alignment siz and Psd3

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_006253101.1
• Gene: Psd3 / 306380
• RGDID: 1559968
• Length: 1296
• Species: Rattus norvegicus
• Alignment Length: 1283
• Identity: 244/1283 - (19%)
• Similarity: 406/1283 - (31%)
• Gaps: 442/1283 - (34%)

  Fly   147 AQQPGSANASTCTDSGSVGGYVYLQNHYAPGAHSS--SAAINY------------------PAQQ 191
            |..|.:| .||....|...|:::      |...:|  ||..|.                  |..|
  Rat    32 APSPTTA-VSTVAPGGLEEGHIF------PSPRTSFFSAPWNVRHSRGLATSPWSLLPEESPGTQ 89

  Fly   192 HPQMVYQIQQYPTCHQ-QQQQQHLQQQQHLHQTGAGHYMQVTATGGGQYHHHHMLHGHGHHAHHH 255
            .|...       .|:. :::::..::..:||           ..|||.....|..||....:...
  Rat    90 RPAAF-------NCYSPKEKKEETEKFPNLH-----------VRGGGVCGSPHSRHGLAPASKKL 136

  Fly   256 G-----------GAVVIAGSGVGTGLGSGATSVIMQH---------------------------- 281
            |           .|..:........:||....||..|
  Rat   137 GLPQQLPCRLASPATTLNDGNSSPSIGSKRWPVISAHEDLWDMDPEARKVIEFSVPQSTLSYASD 201

  Fly   282 ------QQQQQQQQNMHKKNSIRNGGDVLKRTRAQ-----SAYELSQDLLEKQIELLERKYGGVR 335
                  |::......:.:||.....|..:..||||     ...::.|..|
  Rat   202 RGKRALQERGTANSEVLRKNGEEEIGTTVLATRAQLFRYCPIVQIGQSCL--------------- 251

  Fly   336 ARNAAVT--------IQRAFRHYMMVKKFASITAMAKAEKRLSRRMVVTASSL------------ 380
            |..|||.        :..|..|...|.|........|:|::.........|:|
  Rat   252 APPAAVPLKAEPFVWVNNASAHSQSVAKAKYEFLFGKSEEKTPDASDHGGSTLLPPTVTNEFPEY 316

  Fly   381 GLAEEGASSSSAY----GSATESQLTEQQQQQQAQQQQQPRVTIMAGPAGA--ASPGLSRTPPTR 439
            |..||||....|.    ..:....|..||.......|.....::..||.||  ..|......|..
  Rat   317 GTMEEGAEGLRASLDFDAKSPPCHLPGQQAVHLLAGQDSVLNSVTEGPNGAPQCHPQEQSLQPID 381

  Fly   440 SLSMRERRQLDCSPIPRSQSGASPASISSSTVSTSALASHPHVNLLHAAEPHYYNAQALPQGAAY 504
            ||.              |...|:.|.|:|.|...:.:........:|..:.....|...||.|
  Rat   382 SLI--------------SALKATEARIASGTFQATKVLDKDANFSVHRVDKEPRTASHKPQRA-- 430

  Fly   505 YTSYHGSPHDLSYASSADTSLNASWVNTSGHSPH--------TPYYSAAQIYM----RPKGGSTT 557
            :.::...|     ..|.|..|:.........|.|        .|..:.||:..    |.:|....
  Rat   431 HRTFPVGP-----GKSPDRPLSVEVPTEEKFSLHIQEDLTALLPEETPAQLSQITNYRRQGPLHV 490

  Fly   558 PTPSCSGSTGSGSG-------GSGSGSSKKVPPEVPK---RTSSITAQQQTQLLLLQR------- 605
            |..:|..|.||...       |:.......:..|.|:   |..|:..|.:.:.:..|.
  Rat   491 PESACPVSLGSAKNHNSVDRIGALKDQKSDLGRENPRGCDRGGSMGRQTRIKHVEFQGVEILWTG 555

  Fly   606 -----------QTPPPPSLLRT-NGLCKTAENGSLTSVQSSGSDSSVTSAERNLNSDLGSDRSNS 658
                       :|||.    || :.:.|....|...|..::|:.||.|....:::.:...:.|..
  Rat   556 EEVESRHPAGFETPPE----RTASPVRKEFAKGPSHSSSATGACSSSTHLTGSVSDETCKEPSAR 616

  Fly   659 PHTWKRGTA--------------LNSSQQFSTHSADSAG----------AVSGGGVGVAG----- 694
            |.| ..||.              |..|::....:.|..|          .:.||...:.|
  Rat   617 PGT-SLGTLSPVPLGESGEDDVFLRESKEHLEENFDIQGDKERFFKQEEHLRGGDDDILGPGYTE 680

  Fly   695 -GAGVYAAQMQAAVAAATAAGGMPPADDHAI--SSHTSAAQYEQHE-------------QQQHEQ 743
             ...||::|.:..:            |:.::  |:.:....|.:.:             ||:.::
  Rat   681 DSTDVYSSQFETIL------------DNTSLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRIKE 733

  Fly   744 -------------QQLQAAAAAAGVAQNYKMSETIRKRQYRVGLN-------------------- 775
                         ..:.:.:|..|:...|....|       .||:
  Rat   734 GGQFLERTSVGGHHDVLSVSADGGIVMGYSTGIT-------NGLHDPSNSVYTRGPQEIAFWGSS 791

  Fly   776 --LFNK-KP-------EKGITYLIRRGFLENTPQGVARFLITRKGLSRQM----------IGEYL 820
              .|:| ||       |.|.|.::.:...||...|....:...|.|::::          :.::|
  Rat   792 GYCFDKGKPTRLDGNSEMGSTEILEKETTENLSNGTNSNVEAAKRLAKRLYHLDRFKRSDVAKHL 856

  Fly   821 GNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNADIV 885
            |. .|:|:..|...:....|.:|..:|.:||.|...|.:.||.|:.||::..||.||..||.|.:
  Rat   857 GK-NNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERILIHFSNRYFSCNPDTI 920

  Fly   886 GRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMGIYDRVK 950
               .|.|.:..|..|:::||||||..|:  .::|..::||.||:|:::..|..||:|..:|:.:|
  Rat   921 ---TSKDGVHCLTCALMLLNTDLHGHNI--GKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIK 980

  Fly   951 SDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLYEIPDVNKKERP---------GVH 1006
            :::.:..:|                                    |..||:.|         |.|
  Rat   981 NEKLEWAAD------------------------------------DEEKKKSPSEGTDEKANGTH 1009

  Fly  1007 QREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNYPFCIQ-----LSQKV--- 1063
            .:         .|::|.|                  |....||:|:.|....     |::|:
  Rat  1010 PK---------TISRIGS------------------TTNPFLDIPHDPNAAVYKSGFLARKIHAD 1047

  Fly  1064 -DGK--------------IL---ITFNARNEH--DRCKFAEDLKESISEMDEMESLRIEAELE-- 1106
             |||              :|   :.:..::|:  ::....||||.::|....:.|...|.|.:
  Rat  1048 MDGKKTPRGKRGWKTFYAVLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATEYEKKPN 1112

  Fly  1107 --RQKSA-------RNRAPGNAE---NRDSGVADV-EVCPCPYQQGSQ 1141
              :.|:|       :.::|...:   |:.:.||.| ...|.|...|||
  Rat  1113 VFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQ 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	61/227 (27%)
		PH_IQSEC	981..1108	CDD:270128	29/167 (17%)
Psd3	XP_006253101.1	Sec7	830..984	CDD:238100	49/159 (31%)
		PH_EFA6	1029..1154	CDD:270107	24/124 (19%)