Protein Alignment siz and gbf-1

DIOPT Version :9

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: NP_001366879.1
• Gene: gbf-1 / 176609
• WormBaseID: WBGene00007703
• Length: 1975
• Species: Caenorhabditis elegans
• Alignment Length: 657
• Identity: 142/657 - (21%)
• Similarity: 235/657 - (35%)
• Gaps: 143/657 - (21%)

  Fly   689 GVGVAGGAGVYAAQMQAAVAAATAAGGMPPADDHAISSHTSAAQYEQHEQQQHEQQQLQAAAAAA 753
            |:.|..|   |....:.|::....|..||.:....:.|:..|...|.....|..:|:.
 Worm   576 GLPVLSG---YDLAKKMAISTGGKASPMPVSSSIVLRSNRHAPSTELPSMSQIIEQKK------- 630

  Fly   754 GVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQMIGE 818
                        |||....|..|||:.|:|||.:|..:|.|.:..|.:.::|.|...|.::.|.:
 Worm   631 ------------RKRLIAEGTELFNQSPKKGIAFLREKGILGHDEQSLVQWLRTNPQLDKKAIAD 683

  Fly   819 YLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNAD 883
            |:.|.:   :..||:.|.........::|||||.|...||:|||:.:|..:|:.||:.:...|.:
 Worm   684 YICNRK---HAEVLNAFVKSFPFENTRLDVALRMFLETFRLPGESAEIALVMQHFSEEWFRANNE 745

  Fly   884 IVGRLRSSDTIFVLAFAIIMLNTDLHTPNLK-PERRMRVEDFIKNLRGIDDCHDIDKDMLMGIYD 947
            ....:   |..|.|::||||||.|.|.|..| .:..|.|:.|.:||.|.:|..|.|.:||..:|.
 Worm   746 PFFHV---DAAFTLSYAIIMLNVDQHNPQAKRSQPPMTVDCFRRNLSGTNDSRDFDPEMLADMYQ 807

  Fly   948 RVKSDEFKPGSDHVTQVMKVQATIVGKKPNL--ALPHRRLVCYCRLYEIPDVNKKERPGVHQREV 1010
            .:|::|.         ||..:.....|:..:  .|..|........|..|       .|.:..::
 Worm   808 AIKTEEI---------VMPAEQKGTVKEDYMWKVLLRRGETAEGSFYHAP-------TGWNDHDL 856

  Fly  1011 FLF---NDLLVITKIFSKKK-TSVTYTFRNSFPLCGTVVTLLDMPNY--PFCIQLSQKVDGKILI 1069
            |..   ..:..::.:|.|.: ..:.......:..|..:.....|...  ..||.|
 Worm   857 FAVCWGPAVAALSYVFDKSEHEQILQKALTGYRKCAKIAAYYGMKEVFDNLCIHL---------- 911

  Fly  1070 TFNARNEHDRCKFAEDLKESISEM---------DEMESLRIEAELERQKSARNRAPGNAENRDSG 1125
                      |||.     :::.|         ||...|...|.|....|....|....||..:.
 Worm   912 ----------CKFT-----TLTSMRDGGAGGGADEDVDLSAAALLSHSSSPEAVALAFGENHKAQ 961

  Fly  1126 VADVEVCPCPYQQGSQASGEQAPNSADNSQQLKRSALSNSLLDMHEQFGNEK------------- 1177
            :|...:....::.|: ...|...|..:...||.|:.|..:.|...|.:.:||
 Worm   962 LATRTLFYLVHENGN-ILREGWRNLFEALLQLFRARLLPAELTEVEDYVDEKGWVNIQRVHQKEL 1025

  Fly  1178 PQRRGSVGSLD-SGMSISFQSTTTSSASRENAAAIAAAANAAAAAKMRFNMPPTAAIATPSNVYA 1241
            |..|...|.|. .|:............::|..:::..|:...:..:             ||.:.|
 Worm  1026 PHTRNDSGLLSWFGLGGGASEADRRKPTQEQLSSMKLASQVISECR-------------PSQIVA 1077

  Fly  1242 APGMQAYTHANFVQQSQAAYMLQQQQMLQQQAQMQAQAQAQAQAQAQAQAQAQAQAQAQPLTGRI 1306
                    .:.::..:..|.:|                    .:.|...||...||:.|..|..:
 Worm  1078 --------DSKYLTSTSLAELL--------------------SSIAANSAQIVEQAEPQQKTASL 1114

  Fly  1307 PGRERKA 1313
            .|.:..|
 Worm  1115 SGEDEDA 1121

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:279680	66/188 (35%)
		PH_IQSEC	981..1108	CDD:270128	21/141 (15%)
gbf-1	NP_001366879.1	COG5307	354..>998	CDD:227623	116/491 (24%)
		Sec7	631..814	CDD:396096	66/188 (35%)
		PLN03209	<1696..1810	CDD:178748

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910