Protein Alignment siz and step

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_061517935.1
• Gene: step / 1275590
• VectorBaseID: AGAMI1_006207
• Length: 752
• Species: Anopheles gambiae
• Alignment Length: 778
• Identity: 190/778 - (24%)
• Similarity: 315/778 - (40%)
• Gaps: 193/778 - (24%)

  Fly   414 QQPRVTIMAGPAGAASPGLSRTPPTR-------SLSMRERRQ--LDCSPIPRSQSGASPASISSS 469
            |:..|.:.:......|||...|.|||       |.|..||..  ..|..:...:...:..|||::
Mosquito    48 QKSCVDLPSATTNGGSPGPFGTLPTRLDEVVSTSSSTIERPSPACTCEYVQVFEPPETTGSISTT 112

  Fly   470 TVSTSALASHPHVNLLHAAEPHYYNAQALPQGAAYYTSYHGSPHDLSYASSADTSLNASWVNTSG 534
            ...|..::.            |:.:|..|.:.|:       |..:|:.:|:|.:.|..:   .:|
Mosquito   113 ATITKTVSR------------HHQHADKLLESAS-------SDSNLALSSAASSPLEGA---ANG 155

  Fly   535 HSPHTPYYSAAQIYMRPK-----GGSTTPTPSCSGSTGSGSGGSGSGSSKKVPPEVPKRTSSITA 594
            ..|    |:...:..|.:     |..|..|.:                          :|:.:..
Mosquito   156 LQP----YATNSLRRRKEQQVVYGAKTVTTVT--------------------------KTTVLNR 190

  Fly   595 QQQTQLLLLQRQTPPPPSLLRTN----GLCKTAENGSLTSVQSS---GSDSSV---------TSA 643
            |:..::.|:....   ..||.:|    .|.:.::...|.::::.   |..|::         .:.
Mosquito   191 QRTYRVGLIFSDN---GELLNSNLDLRQLVEESKRNFLNALENGVPVGDGSAIPPPPRLAQEPAK 252

  Fly   644 ERNLNSDLGSDRSNSPHTWKRGTALNSSQ-QFSTHSAD--------SAGAVSGGGVGVAGGAGVY 699
            |.|.|..| .:.:..|...::.:.|:.|. .|...|||        ....||...||:
Mosquito   253 EANNNERL-KEAARRPELQQQFSILDDSNFDFIDDSADLFNRNYPHQPPPVSASSVGL------- 309

  Fly   700 AAQMQAAVAAATAAGGMPPADDHAIS---------SHTSAAQYEQHEQQQHEQQ------QLQAA 749
              :.::.|||||:||.   |....|:         .:.|...|::...|.|.:|      ::::.
Mosquito   310 --EPRSLVAAATSAGA---ASTFPITKVLRMCNNCKNRSNLVYQRSCSQPHRKQINDELNEVESE 369

  Fly   750 AAAAGVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQ 814
            ..|....:..|.|.  :.:|..:|...||..|:|||.:|.....|...||.||:||...:||::.
Mosquito   370 MKAHESKEENKHSN--KDKQMALGRKKFNMDPKKGIEFLYENQLLRTDPQDVAQFLYKGEGLNKT 432

  Fly   815 MIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCE 879
            .||:|||. :|.||..||..|....|.:...:..|||:|...||:|||||||:|:||.|:||||:
Mosquito   433 AIGDYLGE-KNDFNEQVLKAFVELHDFTNLILVQALRQFLWSFRLPGEAQKIDRMMECFAQRYCQ 496

  Fly   880 CNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMG 944
            .|.||   ..::||.:||:||||||||.||.|::|  .:..||.||...|||::..|:.:::|..
Mosquito   497 LNPDI---FTNTDTCYVLSFAIIMLNTSLHNPSVK--EKPTVEQFISMNRGINNGGDLPRELLES 556

  Fly   945 IYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLYEIPDVNKKE-------- 1001
            :|:.::::.||...|....:|                        ..:..||   ||
Mosquito   557 LYESIRAEPFKIPQDDGNDLM------------------------HTFFNPD---KEGWLWKQGG 594

  Fly  1002 RPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNYPFCIQL------- 1059
            |....:|..|:.||..:....::..|..     |...||....|..:...:.|.|.:|
Mosquito   595 RYKSWKRRWFILNDNCLYYFEYTTDKEP-----RGIIPLENIAVREVTDRSKPHCFELHASGGAD 654

  Fly  1060 ----------SQKVDGK-ILITFNARNEHDRCKFAEDLKESISEMDEMESLRIEAELERQKSA 1111
                      .:.|:|| .:...:|..|.::.::...|.:|||.....:.|     ::|:|.|
Mosquito   655 IIKACKTDSEGKVVEGKHTVYRMSAATEEEQQEWITRLNQSISHNPFHDIL-----VQRKKKA 712

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	80/187 (43%)
		PH_IQSEC	981..1108	CDD:270128	27/152 (18%)
step	XP_061517935.1	None