| Sequence 1: | NP_730594.1 | Gene: | siz / 40327 | FlyBaseID: | FBgn0026179 | Length: | 1325 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_006411.2 | Gene: | ARFGEF2 / 10564 | HGNCID: | 15853 | Length: | 1785 | Species: | Homo sapiens |
| Alignment Length: | 776 | Identity: | 182/776 - (23%) |
|---|---|---|---|
| Similarity: | 294/776 - (37%) | Gaps: | 210/776 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 342 TIQRAFRHYMMVKKFASITAMAKAEKRLSRRMVVTASSLGLAEEGASSSSAYGSATESQLTEQQQ 406
Fly 407 QQQAQQQQQPRVTIMAGPAGAASPGLSR-----------TPPTRSLSMRERRQLDCSPIPRSQSG 460
Fly 461 ASPASISSSTVSTSALASHPHVNLL---------HAAEPHYYNAQ------------ALPQGAAY 504
Fly 505 YTSYHGSPHDLSYASSADTSLNASWVNTSGHS-----PHT-------PYYSAAQIYMRPKGGSTT 557
Fly 558 PTPSCSGSTGSGSGGSGSGSSKKVPPEVPKRTSSITAQQQTQLLLLQRQTPPPPSLLRTNGLCKT 622
Fly 623 AENGSLTSVQSSGSDSSVTSA----------------------------ERNLNSDLGSDRSNSP 659
Fly 660 HTWKRGTALNSSQQFSTHSADSAGAVSGGGVGVAGGAGVYAAQM------QAAVAAATAAG---G 715
Fly 716 MPPADDHAI--------------------------SSHTSAAQYEQHEQQQHEQQQLQAAAAAAG 754
Fly 755 VAQNYKMS--------------ETIRKRQYRV--GLNLFNKKPEKGITYLIRRGFLENTPQGVAR 803
Fly 804 FLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIER 868
Fly 869 LMEIFSQRYCECNADIVGR--LRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGI 931
Fly 932 DDCHDIDKDMLMGIYDRVKSDEFKPGSDHVTQVMK--VQATIVGK--KPNLALPHRRLVCY 988 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| siz | NP_730594.1 | Sec7 | 766..954 | CDD:279680 | 76/191 (40%) |
| PH_IQSEC | 981..1108 | CDD:270128 | 2/8 (25%) | ||
| ARFGEF2 | NP_006411.2 | DCB, DCB:DCB domain and DCB:HUS domain interaction | 2..224 | 12/83 (14%) | |
| PLN03076 | 11..1711 | CDD:215560 | 182/776 (23%) | ||
| DCB | 28..198 | CDD:292830 | 8/55 (15%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 232..285 | 11/53 (21%) | |||
| Sec7_N | 370..524 | CDD:289549 | 34/192 (18%) | ||
| HUS, DCB:HUS domain interaction | 508..528 | 5/22 (23%) | |||
| Sec7 | 643..827 | CDD:279680 | 76/189 (40%) | ||
| DUF1981 | 1167..1248 | CDD:286414 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1514..1535 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165148865 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5307 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.740 | |||||