Protein Alignment siz and cyth2

DIOPT Version :10

• Sequence 1: NP_730594.1
• Gene: siz / 40327
• FlyBaseID: FBgn0026179
• Length: 1325
• Species: Drosophila melanogaster
• Sequence 2: XP_004916381.1
• Gene: cyth2 / 100379752
• XenbaseID: XB-GENE-5834088
• Length: 405
• Species: Xenopus tropicalis
• Alignment Length: 413
• Identity: 118/413 - (28%)
• Similarity: 194/413 - (46%)
• Gaps: 75/413 - (18%)

  Fly   737 EQQQHEQQQLQAAAAAAGVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGV 801
            |.|:...:..:|.....|:..|.......|.|:..:|...||..|:|||.||.....|.|||:.:
 Frog    32 EIQRLRDELSEAMNEVEGLEANEGSKTLQRNRKMGMGRKKFNMDPKKGIVYLQENELLRNTPEDI 96

  Fly   802 ARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKI 866
            ||||...:||::..||:|||. ::.||::||..|....:.:...:..|||:|...||:|||||||
 Frog    97 ARFLYKGEGLNKTAIGDYLGE-RDDFNISVLHSFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKI 160

  Fly   867 ERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGI 931
            :|:||.|:||||.||.   |..:|:||.:||:||:|||||.||.||::.  :..||.||...|||
 Frog   161 DRMMEAFAQRYCICNP---GVFQSTDTCYVLSFAVIMLNTSLHNPNVRD--KPGVERFISMNRGI 220

  Fly   932 DDCHDIDKDMLMGIYDRVKSDEFK----PGSDHVTQVMKVQATIVGKKPNLALPHRRLVCYCRLY 992
            :|..|:.:::|..:||.::::.||    .|:|                    |.|        .:
 Frog   221 NDGGDLPEELLRNLYDSIRNEPFKIPEDDGND--------------------LTH--------TF 257

  Fly   993 EIPD-----VNKKERPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPN 1052
            ..||     :....|....:|..|:..|..:....::..|..     |...||....:..::.|.
 Frog   258 FNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEP-----RGIIPLENLSIREVEDPR 317

  Fly  1053 YPFCIQL-------------SQKVDGKI------LITFNARNEHDRCKFAEDLKESIS-----EM 1093
            .|.|.:|             ..:.||::      :...:|....::.::.:.:|.::|     ||
 Frog   318 KPNCFELYIPNNKGQLIKACKTEADGRVVEGNHNVYRISAPTPEEKEEWIKSIKAAVSVDPFYEM 382

  Fly  1094 DEMESLRI---EAELERQKSARN 1113
            ......||   :.::::|:..::
 Frog   383 LAARKKRISVKKKQMQQQQQEQS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
siz	NP_730594.1	Sec7	766..954	CDD:460178	83/187 (44%)
		PH_IQSEC	981..1108	CDD:270128	24/158 (15%)
cyth2	XP_004916381.1	Sec7	61..243	CDD:460178	83/187 (44%)
		PH_GRP1-like	258..377	CDD:269954	19/123 (15%)