Protein Alignment CG10584 and Mettl22

DIOPT Version :10

• Sequence 1: NP_649278.1
• Gene: CG10584 / 40324
• FlyBaseID: FBgn0037045
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_001385486.1
• Gene: Mettl22 / 287054
• RGDID: 1311433
• Length: 393
• Species: Rattus norvegicus
• Alignment Length: 295
• Identity: 92/295 - (31%)
• Similarity: 140/295 - (47%)
• Gaps: 75/295 - (25%)

  Fly    42 DKDGDLEVPRPKR--------------------------------------GVIELEHSEATELR 68
            |:||||:|.|..|                                      .:|::||:.||.|.
  Rat   105 DEDGDLDVVRRPRAASDPNPAEPARDKVHPMILEQEEDDLVGDQARESCPYSIIKIEHTMATPLE 169

  Fly    69 LVGLQVWRGALLLADYLFSKKDEFSQKTLMELGAGVGLTSIAAG--IHNNGRIYCTDVDLGCILK 131
            .||.||||||||||||:..::|.|...|::|||||.||.||.|.  .|.   :|||||... :|.
  Rat   170 DVGKQVWRGALLLADYILFRRDLFQGCTVLELGAGTGLASIVAATMAHT---VYCTDVGTD-LLA 230

  Fly   132 LIRGNVQRNSKLLRAT----ISVLEFDFLASKED-----------HSQDLLEAIDNSDIILAADV 181
            :.:.||..| :.|.||    :.|.|.|::  |:|           ..:::.:..|::.::|||:|
  Rat   231 MCQRNVALN-RHLAATGGGVVKVKELDWM--KDDLCTDPKVPFSWSEEEIADLYDHTTVLLAAEV 292

  Fly   182 IYCDTLTDAFICVLDNLLDRGRQTGRPKTIYMALEKRYVFTLEDCDSVAPMYEYLIRQTVNK--- 243
            .|.|.||:|.......|:.|.:..   .|..:::|||:.|||...|.....|:: .|.:::.
  Rat   293 FYDDDLTNALFHTFSRLVHRLKNA---CTAILSVEKRFNFTLRHLDVTCEAYDH-FRASLDSLEK 353

  Fly   244 ------PWIMEHLPLDFPQYFEYDRCKQLVLMKII 272
                  .:::|.:...|||...|:|.:||.|.||:
  Rat   354 LADGRLRFLVEPVETSFPQLLGYERIQQLELWKIV 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10584	NP_649278.1	AdoMet_MTases	70..219	CDD:473071	60/165 (36%)
Mettl22	NP_001385486.1	Nnt1	<174..>322	CDD:443104	56/157 (36%)