Protein Alignment CG10584 and EEF2KMT

DIOPT Version :10

• Sequence 1: NP_649278.1
• Gene: CG10584 / 40324
• FlyBaseID: FBgn0037045
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_958802.1
• Gene: EEF2KMT / 196483
• HGNCID: 32221
• Length: 330
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 68/271 - (25%)
• Similarity: 112/271 - (41%)
• Gaps: 39/271 - (14%)

  Fly    22 KVLSKFRFVYPE------EKLAGIRTDKD---GDLEVPRPKRGVIELEHSEA-TELRLVGLQVWR 76
            :::.|...|:.|      |.||.....|:   |......|..|.:.|..|.| ......||..|.
Human    76 ELIKKHEAVHTEPLDELYEALAETLMAKESTQGHRSYLLPSGGSVTLSESTAIISYGTTGLVTWD 140

  Fly    77 GALLLADYLFSKKDEFSQKTLMELGAGVGLTSIAAGIHNNGRIYCTDVDLGCILKLIRGNVQRNS 141
            .||.||::.......|:.:|::|||:|.|||.:|.......|.|........:|:.:||||..|.
Human   141 AALYLAEWAIENPAVFTNRTVLELGSGAGLTGLAICKMCRPRAYIFSDCHSRVLEQLRGNVLLNG 205

  Fly   142 KLL-----------RATISVLEFDFLASKEDHSQDLLEAIDNSDIILAADVIYCDTLTDAFICVL 195
            ..|           |.|::.|::|.....:      |.|. ..|:::||||:||.....:.:.||
Human   206 LSLEADITAKLDSPRVTVAQLDWDVATVHQ------LSAF-QPDVVIAADVLYCPEAIMSLVGVL 263

  Fly   196 DNLLDRGRQTGRPKTIYMALEKRYVFTLEDCDSVAPMYEYLIRQTVNKPWIMEHLPLDFPQYFEY 260
            ..|. ..|:..|...:|:|      ||:.:.::.......|.|..:.  |.:|  |....:.|.|
Human   264 RRLA-ACREHQRAPEVYVA------FTVRNPETCQLFTTELGRAGIR--WEVE--PRHEQKLFPY 317

  Fly   261 DRCKQLVLMKI 271
            :...::.::.:
Human   318 EEHLEMAMLNL 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10584	NP_649278.1	AdoMet_MTases	70..219	CDD:473071	46/159 (29%)
EEF2KMT	NP_958802.1	FAM86	6..98	CDD:464362	5/21 (24%)
		AdoMet_MTases	135..286	CDD:473071	48/164 (29%)