Protein Alignment CG10584 and METTL23

DIOPT Version :10

• Sequence 1: NP_649278.1
• Gene: CG10584 / 40324
• FlyBaseID: FBgn0037045
• Length: 274
• Species: Drosophila melanogaster
• Sequence 2: NP_001073979.3
• Gene: METTL23 / 124512
• HGNCID: 26988
• Length: 190
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 50/205 - (24%)
• Similarity: 81/205 - (39%)
• Gaps: 55/205 - (26%)

  Fly    72 LQVWRGALLLADYLFSKKDEFSQKTLMELGAGVGLTSIAAGIHNNGRIYCTDVDLGCILKLIRGN 136
            :.||..|::||.||:..:.....|.::|:||||.|..|.|.......|.....:|...|::.|.:
Human     1 MYVWPCAVVLAQYLWFHRRSLPGKAILEIGAGVSLPGILAAKCGAEVILSDSSELPHCLEVCRQS 65

  Fly   137 VQRNS----KLLRATISVLEFDFLASKEDHSQDLLEAIDNSDIILAADVIYCDTLTDAFICVLDN 197
            .|.|:    :::..|...:.:|.|            |:...|||||:||.:   ..:.|..:|
Human    66 CQMNNLPHLQVVGLTWGHISWDLL------------ALPPQDIILASDVFF---EPEDFEDIL-- 113

  Fly   198 LLDRGRQTGRPKTIYMALEKR--------YVFTLEDCDSVAPMYEYLIRQTVNKPWIME--HLPL 252
                       .|||..:.|.        |.....|....|.:|:          |.|:  |:||
Human   114 -----------ATIYFLMHKNPKVQLWSTYQVRSADWSLEALLYK----------WDMKCVHIPL 157

  Fly   253 DFPQYFEYDR 262
               :.|:.|:
Human   158 ---ESFDADK 164

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10584	NP_649278.1	AdoMet_MTases	70..219	CDD:473071	39/158 (25%)
METTL23	NP_001073979.3	AdoMet_MTases	3..126	CDD:473071	39/150 (26%)