Protein Alignment CG12983 and dnai7

DIOPT Version :10

• Sequence 1: NP_001137992.1
• Gene: CG12983 / 40319
• FlyBaseID: FBgn0037040
• Length: 1104
• Species: Drosophila melanogaster
• Sequence 2: XP_005164821.1
• Gene: dnai7 / 566485
• ZFINID: ZDB-GENE-041210-153
• Length: 731
• Species: Danio rerio
• Alignment Length: 1187
• Identity: 191/1187 - (16%)
• Similarity: 336/1187 - (28%)
• Gaps: 552/1187 - (46%)

  Fly     5 KNQDAVSIKPAVELLSEEEWMARRNIYMQRL-ADLKTSVAFIDDAVEEYK----ELQKQKLRND- 63
            |.:..:|......|..|||...:|.....|| |:.:.:.....:.:|:.|    ||:.::.|.|
Zfish    10 KKKGGISKAEKERLQREEEEKRQREAEEARLIAEREENERLERERIEQEKQHILELKDRERREDE 74

  Fly    64 --------------------------KWNSYLACDGLPNPSRPAEIRKFIFQLNFMEQESCANEI 102
                                      ||..|:.|||.|:||...||..:|    .:.::...|:|
Zfish    75 LNELRHILDENHFAVTVWEAECREKSKWERYMLCDGSPDPSVQPEINTYI----SLWRDDSENQI 135

  Fly   103 SWVLSVDECSVLSQAPDRCDRTRKIMEKSRPNVGQLYDETVQRILATIERVQRVLRNDDELVHLP 167
            ..||  :||::..:.....|..  :.:...|::.:.|.||:..:              ..|:|.
Zfish   136 QKVL--EECALTLELEKELDFL--LGDGPEPSIAEQYQETLLSL--------------QNLIHY- 181

  Fly   168 TFQVRELDKIPNEL--YGEIESFFDKLTYRVVSSPDALMMNKDSILSCYCYKCSNFDLEIWGLQD 230
                 :|::...||  :....|..|....:.|                  .|.:|..|.:|...:
Zfish   182 -----KLNQATEELLKFANYNSDIDTGNMQTV------------------VKDNNITLCLWANLN 223

  Fly   231 VPIRFNYLKLPVMCSDLNCVGVTIQLPLSVLCDNLTLRCVRTFFDPLSHLAKSFELVIDSSVIPN 295
            ...||...|...       ||:..:||..:....:.:|.:.|.:|.|||
Zfish   224 KNPRFKGYKFEE-------VGLGFELPKPLAVIEVAVRILHTRYDHLSH---------------- 265

  Fly   296 CGLVDIADSVMSEWMTQMDIQEDLVVKMETEMRAYNEAIAFIAQAEAKEKRKSQKKKIAIPKPPK 360
                                                     .::.|..:||:|..:.
Zfish   266 -----------------------------------------HSEREQLQKRRSMMEA-------- 281

  Fly   361 MPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYFHPGNINLLPSEVNLRRFIILGGIVSLVFVGKA 425
                                                                             
Zfish   282 ----------------------------------------------------------------- 281

  Fly   426 KHASYEKFNITLHEDGRVLRKSLNILDESSTEECSMQPSKLDIGTDIMRDTEVGEASKIPLHLEP 490
                                    ||.:::....::...|:
Zfish   282 ------------------------ILTQNTESSAAVHNGKM------------------------ 298

  Fly   491 DELPYYFLTFKVPNHLCLWGEPIVCQFFESEIEETPSKAKAEELDKKLDKKKKPVRKSSRKENES 555
                                        |.|.:|:.|..:.||...        ||..|||.
Zfish   299 ----------------------------EGERDESESSKQVEECHS--------VRSESRKR--- 324

  Fly   556 VLRVPTTSGSVSMSEEKPPQSNRPTYHQPARENSVNIYRPSALTIVRQSGMETEQIQYKKTFKNS 620
                                                    ||::::.
Zfish   325 ----------------------------------------SAVSVIS------------------ 331

  Fly   621 NLVKEPISKRNLSLLQDQCLPRIISSLRFPRDFQDDKMEAQAMKKIPVTQLYKRQLTESVGSTQI 685
              .||.....::.||::                                           |.:|:
Zfish   332 --AKEGRKSSSVKLLEE-------------------------------------------GESQM 351

  Fly   686 EKFSFNYE-DQSNPERLYPK--FPVTEDLRVETDRTDSSKEEGTMLGLL------------RTLE 735
            |:.:...| ||.:|   ||.  .|||     :||......::.|.||.:            ||::
Zfish   352 EEITTTLESDQHDP---YPSPAEPVT-----DTDVHIVDLQQFTPLGGVFYFDLFHMPPQSRTVK 408

  Fly   736 GIK-DKYLDAPKRIVEQTTHAVRMSRKAYSDPIPTTRSRRQSYFGRRSVRQLDSSIMSIARPVDI 799
            |.: .:.||...::.                |.||.:||.||          .:|:
Zfish   409 GWEMRELLDTGLQVF----------------PYPTEQSRIQS----------STSV--------- 438

  Fly   800 EYELSETSDTGEQMIKSRKDSRLPSTILSQSAEPRNA------AHWTTEFILESSFNKESKVVIV 858
              :|.|.|:|....:.......||.::|... :|:.|      .||.|:.|.|:|::.||:.:..
Zfish   439 --KLDEHSNTTVASLPVGVTVALPHSVLFLE-DPQVARWDPIGQHWRTDCISETSYDAESRTISF 500

  Fly   859 KTDRLGHFGFAYRRYAHFPFRHWELEKNEQNHDEIILTLDTYHVRVVFFISKDGIRC--HAIDIP 921
            :......|......||:.||:.|||....|  |..:.|:....:.|  .|:..|.:|  |..:..
Zfish   501 QMTAFYAFTLLQETYANMPFQSWELRPLGQ--DSALFTITGALIEV--SITVKGKQCMLHTEETK 561

  Fly   922 KEYVHRPFKYIDIDKPISDFV---ELRKRLQDMNLNVFAELDACFYIDQGYFSQKHLAAELH--- 980
                       |:|..:..::   ||:|.::...:|:|.          ..:|.|:::..|.
Zfish   562 -----------DLDHLLGKWMSPSELQKAMRKAGINIFV----------NEYSDKYVSINLKDPL 605

  Fly   981 ----IYDAIAVHGKLMKFSRSQWNRLAKDRDLVL--CLQNTRDIHDGSEVTVRVTPEVSTFVDVS 1039
                :|:.:|:....:.||.|:||...:...|||  |.|            :.|.|.......:.
Zfish   606 IEHAVYEQMALMSSAVAFSWSRWNAQCRQEHLVLQACEQ------------MEVGPVAEEAWSLY 658

  Fly  1040 ELCSDDTKVIKL---------------NYKSTWRNMGTYSDLHQLINSMYPQATDMRNRDANQMY 1089
            .|.:...:.:|:               .:.||:        ||.|...|..:. ..|.|.::.:|
Zfish   659 LLGAQRNQHLKMKEQEDSFSPELAEGSEFHSTF--------LHMLRQDMSTEG-QARVRQSHHLY 714

  Fly  1090 Y--IRQLLQEIRPLSFS 1104
            .  :::||...|.|::|
Zfish   715 IDTVQRLLCATRVLTYS 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12983	NP_001137992.1	Casc1_N	17..152	CDD:464947	37/166 (22%)
		Casc1_C	838..1056	CDD:432508	50/246 (20%)
dnai7	XP_005164821.1	Casc1_N	62..227	CDD:464947	39/210 (19%)
		Casc1_C	480..>639	CDD:432508	42/183 (23%)