Protein Alignment CG12983 and Dnai7

DIOPT Version :10

• Sequence 1: NP_001137992.1
• Gene: CG12983 / 40319
• FlyBaseID: FBgn0037040
• Length: 1104
• Species: Drosophila melanogaster
• Sequence 2: XP_038963394.1
• Gene: Dnai7 / 297720
• RGDID: 1311213
• Length: 767
• Species: Rattus norvegicus
• Alignment Length: 870
• Identity: 166/870 - (19%)
• Similarity: 314/870 - (36%)
• Gaps: 214/870 - (24%)

  Fly   343 KEKRKSQKKKIAIPKPPKMPQELPAGMFPDPRKIFLEHEKRDCTDFFNRYFHPGNINLLPSEVN- 406
            |:|:...||||...:..::.||.......:..:..|::||.:......:.......|||..:||
  Rat     4 KQKKAPTKKKITKAERLRLLQEEEEKRLKEEEEARLKYEKEEQERLEKQRIEREKWNLLEKKVNK 68

  Fly   407 ----LRRFIILG---GIVSLVFV--GKAKHASYEKFNITLHEDGRVLRKSLNILDESSTEECSMQ 462
                |..:.:|.   .:.|..|.  |.:.|..::.           |.:....|:|.:..||...
  Rat    69 YECQLGCYPLLHWGCSVPSPAFTACGASPHMCFQD-----------LERRSEELEELALLECCFP 122

  Fly   463 PSKLDIGTDIMRDTEVGEASKIPLHLEPDELPYYFLTFKVPNHLCLWGEPIVCQFFESEIEETPS 527
            .::       .:..|:...::...:.|.|..|...:..::...:.||.|. ..:.||..:|:  |
  Rat   123 EAE-------KQKREMRVLAQWKHYTECDGSPDPRIAQEMNTFISLWEEE-KNETFEQVMEK--S 177

  Fly   528 KAKAEELDK-KLDKKKKPVRKSSRKENESVLRVPTTSGSVSMSEEKPPQSNRPTYHQPARENSVN 591
            |.....::| ||...:.|   |...:..:||:.   .||:...:|             .....||
  Rat   178 KLVLSLIEKLKLILLETP---SCDLDKSTVLQY---QGSILRLQE-------------LLSLKVN 223

  Fly   592 IYRPSALTIVRQSG----METEQIQYKKTFKN--------SNLVKEPISKRNLSLLQDQC---LP 641
            :   :...::||:.    ::|..::  |..|:        :||.|.| ..|.:...|.|.   :|
  Rat   224 V---ATELLLRQASNLADLDTGNME--KIIKDENVTLYVWANLKKNP-RYRTVKFSQTQVGFEIP 282

  Fly   642 RIIS----SLRFPRDFQDDKMEAQAMKKIPVTQLYKRQLTESV-GSTQIEKFSFNYEDQSNPERL 701
            ||::    :||......|.           :|.|:...:||.. ||...|    |::::...|:.
  Rat   283 RILATSNVALRLLHTHYDH-----------ITPLFSTVVTEEKHGSIVAE----NFKEEERTEKA 332

  Fly   702 YPKFPV--------TEDLRVETDRTDSS--KEEGTMLGLLRTLEGIKDKYLDAPKRIVEQTTHAV 756
            .|:..|        .|.|:.|.:|..||  :||   :....|::.:..|..| |:....|||. .
  Rat   333 VPEENVFTEEAADEAEQLKAEEERELSSIPEEE---VKFDPTVDTVTQKISD-PEEEESQTTQ-F 392

  Fly   757 RMSRKAYSDPIPTTRSRRQSYFGRRSVRQLDSSIMSIARPVDIE-YE------------------ 802
            .:.||..|:.:              |..||......:..|..:| ||
  Rat   393 ELERKLLSETV--------------SAAQLSLIENVLEMPETLEPYEVNMCHFAPLGGVYHLEIL 443

  Fly   803 -------------LSETSDTG--------EQMIKSRKDSRLP----STILSQSA----EPR---- 834
                         |:|....|        |...:...:|..|    :..:.:||    :|:
  Rat   444 ELPPQSKPVKGWVLAEIRQEGLQKFTYPPENTEEPDPESAFPPIEVTLEIHESAIFFEDPQVVRW 508

  Fly   835 --NAAHWTTEFILESSFNKESKVVIVKTDRLGHFGFAYRRYAHFPFRHWELEKNEQNHDEIILTL 897
              ....|.::.:....:|:|::::....|.:|........:.:.|::.|||.....|  :.:|.:
  Rat   509 DAEGKFWRSDGVTCVYYNRENRLLTFSIDTMGPVTLIQDAHVNMPYQSWELSPLGMN--KALLMV 571

  Fly   898 DTYHVRVVFFISKDGIRCHAIDIPKEYVHRPFKYIDIDKPISDFVELRKRLQDMNLNVFAELDAC 962
            .|..:.:...|.:  ..|....:..:...|..:.|........|:   ..|::..||:|..:.:.
  Rat   572 TTVFIELQIHIKE--THCMLAAVKLKGKSRELRVIGKWMTPIPFI---LALKEAGLNIFPAVYSH 631

  Fly   963 FYIDQGYFSQKHLAAELHIYDAIAVHGKLMKFSRSQWNRLAKDRDLVLCLQNTRDIHDGSEVTVR 1027
            ||:   ..:.|....||..|..:|:......|..|:||        ::|        :.:.|..|
  Rat   632 FYV---VVNNKVPQMELKAYRQMALLSSAFSFGWSKWN--------MVC--------NSTRVVFR 677

  Fly  1028 VTPEVSTFVDVSE-----LCSDDTKVIKLNYKSTW--RNMGTYSDLHQLINSMY-----PQATD- 1079
            |...:|...:.:.     ...|..:::|:..:|..  ..:...|:.|..:..|.     |:||:
  Rat   678 VREHISEEEEQNTWALLMFSGDRAQMLKMQEESDQFSETLREGSEFHSTLYHMMKDFASPEATEK 742

  Fly  1080 MRNRDANQMYYIRQLLQEIRPLSFS 1104
            :|:.:...:..:..:|..:|.||:|
  Rat   743 VRHSNCQFIDSVCYMLLSVRVLSYS 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12983	NP_001137992.1	Casc1_N	17..152	CDD:464947
		Casc1_C	838..1056	CDD:432508	39/222 (18%)
Dnai7	XP_038963394.1	Casc1_N	37..266	CDD:464947	52/274 (19%)