Protein Alignment CG12983 and K09E2.2

DIOPT Version :9

• Sequence 1: NP_001137992.1
• Gene: CG12983 / 40319
• FlyBaseID: FBgn0037040
• Length: 1104
• Species: Drosophila melanogaster
• Sequence 2: NP_509468.3
• Gene: K09E2.2 / 187216
• WormBaseID: WBGene00019571
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 685
• Identity: 129/685 - (18%)
• Similarity: 229/685 - (33%)
• Gaps: 224/685 - (32%)

  Fly   516 QFFESEI--EETPSKAKAEELDKKLDKKKKPVRKSSRKENESVLRVPTTSG--SVSMSEEKPPQS 576
            ::.|.:|  :.|..|:........||.:.....:.:.|..:.:::..|.|.  |:..::.|
 Worm    33 RYVEGDILYDVTDEKSANTVHSYVLDPENNLSLEDTHKYFDYIMKALTNSSVDSIDKTDSK---- 93

  Fly   577 NRPTYHQPARENSVNIYRPSALTIVR--------QSGMETEQIQYKKTFKNSNLVKEPISKRNLS 633
                :.|...:| :||::.....:::        |.|:|:          |.|.:...:....||
 Worm    94 ----WLQLVAQN-MNIFQDVKSKLLKRWTWLVFEQCGIES----------NKNEIIFQLESLTLS 143

  Fly   634 L----------------LQDQCLPRIISSLRFPRDFQDDKMEA-QAMKKIPVTQLYKRQLTESVG 681
            .                :..:.:| .:.|:|..:.|:....|. ..|||.|:..||:
 Worm   144 FWRASSERKGKIIFFPGIHIEIVP-FLQSIRVVQHFEQHTTELHNVMKKYPLEFLYQ-------- 199

  Fly   682 STQIEKFSFNYEDQSNPERLYPKFPVTEDLRVETDRTDSSK--EEGTMLGLLRTLE-----GIKD 739
                     ..|.:.:||   |...:..|:.||.......|  ::....||..|:|     |.|.
 Worm   200 ---------YVEPEEDPE---PYDELVPDIFVENKLVTKKKLRKKVVKKGLTNTIELALKSGEKR 252

  Fly   740 K----------------------------YLD---------APKRIVEQTTHAVRMSRKAYSDPI 767
            |                            |.|         ..:|..:.|.|.:....:|:..|:
 Worm   253 KKKQAHLSQRTLLSRSPSLKRGEHIRFNLYSDVTPIWKKSATKERSTDGTEHKIDFGTEAFLGPV 317

  Fly   768 PTTRSRRQSYFGRRSVRQLDSSIMSIARPVDIEYELSETSDTGEQMIKSRKDSRLP-STILSQSA 831
            ....|...|    :..::..|..::      |:.:|.|...:||.::.|.|   :| ..:...|.
 Worm   318 YLISSFESS----KKTQKYGSWTLT------IDVKLDERKLSGESLLVSLK---VPVEEVFLGSN 369

  Fly   832 EP------RNAAHWTT-EFILESSFNKESKVVIVKTDRLGHFGFAYRRYAHFPFRHWELEKNEQN 889
            ||      ..:..|.. .|...:.|::.:.:|..:..::|:.........|:|::.|::...:
 Worm   370 EPVVAFRDETSTDWKKGVFTTHTQFDQNTFIVTTRLSKMGYVSLFQHNDFHYPYKSWKILFEQ-- 432

  Fly   890 HDEIILTLDTYHVRVVFFISKDGIRCHAIDIPKEYVHRPFKYIDIDKPISD-FVELRKRLQ-DMN 952
             |:|.|.|.|..|.:.|.|..:                   |..:|....| |.:||...| .|:
 Worm   433 -DKISLRLHTNVVELAFVIEGN-------------------YFYLDTLTGDEFSKLRNLHQKKMS 477

  Fly   953 LNVFAELDACFYIDQGYFSQKHLAAELHIY---DAIAVHGKLMKFSRSQWNRLAKDRDL------ 1008
            |   :||...|        :||   .:||.   |.|..|           ....||.||
 Worm   478 L---SELIMKF--------EKH---GVHIVPNDDIINKH-----------RDTKKDLDLEIFTYR 517

  Fly  1009 VLCLQ--NTRDIHDGSEVTVRVTPEVSTFVDVSELCSDDTKVIKLNYKSTWRNMGTYSDLHQLIN 1071
            ::||.  |.......|.|::                  :|.|:.:|  ...||:.|.|....::|
 Worm   518 LICLNQINCESCRMNSTVSM------------------ETVVLTVN--GAPRNITTKSAGKYVVN 562

  Fly  1072 SMYPQATDMRNRDANQMYYIR-----QLLQEIRPL 1101
              :.:|...:....|   |:.     |.|...|||
 Worm   563 --FGEAGKKQRIHEN---YVTPATLFQFLMVTRPL 592

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12983	NP_001137992.1	Casc1	253..515	CDD:289161
		Casc1	839..1054	CDD:289161	47/228 (21%)
K09E2.2	NP_509468.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR20929
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030