DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10587 and Tmprss11c

DIOPT Version :10

Sequence 1:NP_001137989.2 Gene:CG10587 / 40318 FlyBaseID:FBgn0037039 Length:289 Species:Drosophila melanogaster
Sequence 2:NP_001025468.1 Gene:Tmprss11c / 435845 MGIID:3521861 Length:431 Species:Mus musculus


Alignment Length:273 Identity:81/273 - (29%)
Similarity:128/273 - (46%) Gaps:40/273 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 LAQDLNQTIDVNKLAKIVQRPGFQTRVVGGDVTTNAQLGGYLIALRYEMNFV--CGGTLLHDLIV 82
            :|:||..|....:  .|:.|   ..:|.||.   :|:.|.:......:.|.|  ||.||:.:..:
Mouse   179 IAEDLLNTCCGRR--TIIHR---GHKVAGGQ---DAEEGEWPWQASLQQNSVHRCGATLISNYWL 235

  Fly    83 LTAAHCFLGRVKISDWLAVGGASKLNDRGIQRQVKEVIKSAEFREDDMNMDVAILRLKKPMKGKS 147
            :||||||:......|| .|.....|:.....|.||.:|....:.....:.|:|::||..|:..:|
Mouse   236 ITAAHCFIRAANPKDW-KVSFGFLLSKPQAPRAVKNIIIHENYSYPAHDNDIAVVRLSSPVLYES 299

  Fly   148 -LGQLIL--CKKQLMPGTELRVSGWGLTENSEFGPQKLLRTVTVPVVDKKKCRASYLPTDWESHK 209
             :.:..|  ..::..|.:::.|:||| |..|:.....:|:...|.::|.|.|.:.          
Mouse   300 NIRRACLPEATQKFPPNSDVVVTGWG-TLKSDGDSPNILQKGKVKIIDNKTCNSG---------- 353

  Fly   210 HFDLFLKVH---LTDSMFCAGVL-GKKDACTFDSGGPLVYKNQ-----VCGIVSFGIGCASKRYY 265
                  |.:   :|..|.|||.| |:.|||..|||||||.::.     :.||||:|..||.....
Mouse   354 ------KAYGGMITPGMMCAGFLKGRVDACQGDSGGPLVSEDSKGIWFLAGIVSWGDECALPNKP 412

  Fly   266 GVYTDIMYVKPFI 278
            ||||.:.|.:.:|
Mouse   413 GVYTRVTYYRDWI 425

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10587NP_001137989.2 Tryp_SPc 45..278 CDD:214473 74/246 (30%)
Tmprss11cNP_001025468.1 SEA 62..161 CDD:460188
Tryp_SPc 200..428 CDD:238113 75/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.