Protein Alignment CG10587 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_001137989.2
• Gene: CG10587 / 40318
• FlyBaseID: FBgn0037039
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 76/293 - (25%)
• Similarity: 121/293 - (41%)
• Gaps: 58/293 - (19%)

  Fly    24 LNQTIDVNKLAKIVQRPGFQTRVVG---GDVTTNAQLGGYLI----------------------A 63
            |||.|. |..|..:.....|...:.   |::|..|..|..::                      :
Human   143 LNQKIR-NLRALPINASSVQVNAMSSSTGELTVQASCGKRVVPLNVNRIASGVIAPKAAWPWQAS 206

  Fly    64 LRYEMNFVCGGTLLHDLIVLTAAHCFLGRVKISDWLAVGGASKLNDRGIQRQVKEVIKSAEFRED 128
            |:|:....||.||:.:..::||||||........| .|...:|:|...::|.|:..|...::|..
Human   207 LQYDNIHQCGATLISNTWLVTAAHCFQKYKNPHQW-TVSFGTKINPPLMKRNVRRFIIHEKYRSA 270

  Fly   129 DMNMDVAILRLKKPMK-GKSLGQLIL--CKKQLMPGTELRVSGWG-LTENSEFGPQKLLRTVTVP 189
            ....|:|::::...:. ...:.|:.|  ......|...:.::|:| |....|  .|..||...|.
Human   271 AREYDIAVVQVSSRVTFSDDIRQICLPEASASFQPNLTVHITGFGALYYGGE--SQNDLREARVK 333

  Fly   190 VVDKKKCRASYLPTDWESHKHFDLFLKVHLTD---SMFCAGVL-GKKDACTFDSGGPLVYKN--- 247
            ::....|:..                :|:..|   .|||||.: |..|||..|||||||.::
Human   334 IISDDVCKQP----------------QVYGNDIKPGMFCAGYMEGIYDACRGDSGGPLVTRDLKD 382

  Fly   248 --QVCGIVSFGIGCASKRYYGVYTDIMYVKPFI 278
              .:.||||:|..|..|...||||.:.|.:.:|
Human   383 TWYLIGIVSWGDNCGQKDKPGVYTQVTYYRNWI 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10587	NP_001137989.2	Tryp_SPc	45..278	CDD:214473	68/270 (25%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188	4/6 (67%)
		Tryp_SPc	190..418	CDD:238113	65/245 (27%)