DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10587 and TMPRSS11E

DIOPT Version :10

Sequence 1:NP_001137989.2 Gene:CG10587 / 40318 FlyBaseID:FBgn0037039 Length:289 Species:Drosophila melanogaster
Sequence 2:NP_054777.2 Gene:TMPRSS11E / 28983 HGNCID:24465 Length:423 Species:Homo sapiens


Alignment Length:249 Identity:70/249 - (28%)
Similarity:120/249 - (48%) Gaps:29/249 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 GFQTRVVGGDVTTNAQLG--GYLIALRYEMNFVCGGTLLHDLIVLTAAHCFLGRVKISDWLAVGG 103
            |...|:|||   |..:.|  .:..:|:::.:..||.||::...:::|||||......:.|.|..|
Human   187 GQSLRIVGG---TEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFG 248

  Fly   104 ASKLNDRGIQRQVKEVIKSAEFREDDMNMDVAILRLKKPMK-GKSLGQLIL--CKKQLMPGTELR 165
            .: :....::|.::.:|...:::....:.|:::..|..|:. ..::.::.|  ...:..||..:.
Human   249 VT-IKPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPYTNAVHRVCLPDASYEFQPGDVMF 312

  Fly   166 VSGWGLTENSEFGPQKLLRTVTVPVVDKKKCRASYLPTDWESHKHFDLFLKVHLTDSMFCAGVL- 229
            |:|:|..:|..:. |..||...|.::|...|.        |...:.|.     :|..|.|||.| 
Human   313 VTGFGALKNDGYS-QNHLRQAQVTLIDATTCN--------EPQAYNDA-----ITPRMLCAGSLE 363

  Fly   230 GKKDACTFDSGGPLVYKN-----QVCGIVSFGIGCASKRYYGVYTDIMYVKPFI 278
            ||.|||..|||||||..:     .:.||||:|..||.....||||.:..::.:|
Human   364 GKTDACQGDSGGPLVSSDARDIWYLAGIVSWGDECAKPNKPGVYTRVTALRDWI 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10587NP_001137989.2 Tryp_SPc 45..278 CDD:214473 68/243 (28%)
TMPRSS11ENP_054777.2 SEA 51..147 CDD:460188
Tryp_SPc 192..420 CDD:238113 68/244 (28%)
Blue background indicates that the domain is not in the aligned region.

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