Protein Alignment CG10587 and PRSS21

DIOPT Version :10

• Sequence 1: NP_001137989.2
• Gene: CG10587 / 40318
• FlyBaseID: FBgn0037039
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 309
• Identity: 87/309 - (28%)
• Similarity: 133/309 - (43%)
• Gaps: 59/309 - (19%)

  Fly     2 QGLLLYCLLTAPLASIEVLAQDLNQTIDVNKLAKIVQRPGFQTRVVGGDVTTNAQLG--GYLIAL 64
            :|.||..||.|.....:..:|      :...|:....|....:|:|||:   :|:||  .:..:|
Human     4 RGALLLALLLARAGLRKPESQ------EAAPLSGPCGRRVITSRIVGGE---DAELGRWPWQGSL 59

  Fly    65 RYEMNFVCGGTLLHDLIVLTAAHCFLGRVKISD---WLAVGG--ASKLNDRGIQRQ-----VKEV 119
            |...:.|||.:||.....|||||||.....:||   |:...|  .|..:...:|..     |..:
Human    60 RLWDSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNI 124

  Fly   120 IKSAEFREDDMNMDVAILRLKKPMKGKSLGQLILCKKQLMP------------GTELRVSGWGLT 172
            ..|..:. .:...|:|:::|..|         :...|.:.|            .|:..|:|||..
Human   125 YLSPRYL-GNSPYDIALVKLSAP---------VTYTKHIQPICLQASTFEFENRTDCWVTGWGYI 179

  Fly   173 ENSEFGPQ-KLLRTVTVPVVDKKKCRASYLPTDWESHKHFDLFLKVHLTDSMFCAG-VLGKKDAC 235
            :..|..|. ..|:.|.|.:::...|...:|...:..    |:|      ..|.||| ..|.||||
Human   180 KEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRK----DIF------GDMVCAGNAQGGKDAC 234

  Fly   236 TFDSGGPLV-YKNQV---CGIVSFGIGCASKRYYGVYTDIMYVKPFIEQ 280
            ..||||||. .||.:   .|:||:|:||......||||:|.:...:|::
Human   235 FGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHFEWIQK 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10587	NP_001137989.2	Tryp_SPc	45..278	CDD:214473	77/262 (29%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	77/263 (29%)