DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10588 and QCR2

DIOPT Version :9

Sequence 1:	NP_001287135.1	Gene:	CG10588 / 40316	FlyBaseID:	FBgn0037037	Length:	1058	Species:	Drosophila melanogaster
Sequence 2:	NP_015517.1	Gene:	QCR2 / 856321	SGDID:	S000006395	Length:	368	Species:	Saccharomyces cerevisiae

Alignment Length:	450	Identity:	91/450 - (20%)
Similarity:	156/450 - (34%)	Gaps:	151/450 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 RASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQY---QGLAHFVEHMIFMGSE-----KFPVE 132
            :.|...|..|..:...|::..||.|..||     :|   .|:||.:....|..:.     |...|
Yeast    11 QGSVRRLTVSARDAPTKISTLAVKVHGGS-----RYATKDGVAHLLNRFNFQNTNTRSALKLVRE 70

  Fly   133 NEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMNLMKAPL-------------MLP 184
            :|.      .||...:..:.|    |..|..|.|...:..::|.:...|             :||
Yeast    71 SEL------LGGTFKSTLDRE----YITLKATFLKDDLPYYVNALADVLYKTAFKPHELTESVLP 125

  Fly   185 ----DAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTLKEGVDDSSLHK 245
                |....|:..|:|           ..||:.|....:|.       || ..|.:||:
Yeast   126 AARYDYAVAEQCPVKS-----------AEDQLYAITFRKGL-------GN-PLLYDGVE------ 165

  Fly   246 ELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQKAFRDQFYKD 310
                                 ::||.::::.     ||...:::| ::||..|..:|...:|..:
Yeast   166 ---------------------RVSLQDIKDF-----ADKVYTKEN-LEVSGENVVEADLKRFVDE 203

  Fly   311 VFLVQPVEDVCKLELTWVLPPMKNFY-RSKPDMFISQ-----LIG--YEGVG------SLCAY-- 359
                         .|...||..|:.. :|:|..|:.:     .||  ...:|      ||..|
Yeast   204 -------------SLLSTLPAGKSLVSKSEPKFFLGEENRVRFIGDSVAAIGIPVNKASLAQYEV 255

  Fly   360 LRHHLW-CISVVAGVAESS----FDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKL----- 414
            |.::|. .:|.::|:..|:    |....:::||     :.|.....:...::...|.:|.
Yeast   256 LANYLTSALSELSGLISSAKLDKFTDGGLFTLF-----VRDQDSAVVSSNIKKIVADLKKGKDLS 315

  Fly   415 -IINSDQLQDSYKE---SQQIENNNFRFQIEPPPIDHVQSI-VESFNYLPSKDVLTGPQL 469
             .||..:|:::.:.   |..||.|          .|.|:.. :..|||:...||...|.|
Yeast   316 PAINYTKLKNAVQNESVSSPIELN----------FDAVKDFKLGKFNYVAVGDVSNLPYL 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	90/449 (20%)
		Peptidase_M16	85..214	CDD:279066	32/153 (21%)
		Peptidase_M16_C	244..419	CDD:282978	36/201 (18%)
		Peptidase_M16_M	436..720	CDD:292805	8/34 (24%)
		Peptidase_M16_C	724..907	CDD:282978
QCR2	NP_015517.1	PqqL	1..362	CDD:223685	89/445 (20%)
QCR2	NP_015517.1	Peptidase_M16	17..163	CDD:395547	38/179 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343062
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840