Protein Alignment CG10588 and AXL1

DIOPT Version :9

• Sequence 1: NP_001287135.1
• Gene: CG10588 / 40316
• FlyBaseID: FBgn0037037
• Length: 1058
• Species: Drosophila melanogaster
• Sequence 2: NP_015447.1
• Gene: AXL1 / 856240
• SGDID: S000006326
• Length: 1208
• Species: Saccharomyces cerevisiae
• Alignment Length: 1176
• Identity: 257/1176 - (21%)
• Similarity: 456/1176 - (38%)
• Gaps: 315/1176 - (26%)

  Fly    47 SKLYRALTLSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQY 111
            ::.::...|.||:.|::|||.                :.|.      ::|::.|..||.::|:..
Yeast    21 NRTHKVCKLPNGILALIISDP----------------TDTS------SSCSLTVCTGSHNDPKDI 63

  Fly   112 QGLAHFVEHMIF-MGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTH------LDRG 169
            .||||..||||. .||:|:|....|.:.:.|:.|..||.|..|:|.|||||..|.      .:..
Yeast    64 AGLAHLCEHMILSAGSKKYPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESI 128

  Fly   170 MDLFMNLMKAPLMLPDAMSRERSAVQSEFE-----QTHMRDEVRRDQILASLASEGYPHGTFSWG 229
            :|:|.:..|.||..|..:|:|..|:|||.|     .|.:.....|     .||:..:|...||.|
Yeast   129 LDVFASFFKEPLFNPLLISKEIYAIQSEHEGNISSTTKIFYHAAR-----ILANPDHPFSRFSTG 188

  Fly   230 NYKTLKE--GVDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADI-PTS--QQ 289
            |..:|..  .:....|...|:.::.:::....:.:.::...|::.|.:|.:....|| |.|  ::
Yeast   189 NIHSLSSIPQLKKIKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSAVKE 253

  Fly   290 NSI-----------------DVSQLNYQ--KAFR------DQFYKDVFLVQPVEDVC-------- 321
            .||                 |.|:.:|.  |.|:      ::.||:....|...: |
Yeast   254 RSISIRTRSFRRSKSLKKRQDSSKNDYSDLKTFKILNTTWEKKYKNTMCFQQFPE-CNSIFINSN 317

  Fly   322 KLELTWVLPPM--KNFYRSKPDMFI-----SQLIGYEGVGSLCAYLRHHLWCISVVAGVAESSF- 378
            |:.:..:|.|:  ||...:|.|:.|     .:|.|.|..|||..||....|.....|..:|.:.
Yeast   318 KVPIMRLLFPVSDKNTRFTKDDIKIYSHLWCELFGDESPGSLSYYLASKGWLTGCFAFTSEFAIG 382

  Fly   379 DSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKL-----IINSDQLQDSYKESQQIENNNFRF 438
            |...|..|     .|::.|:::|..:  .|....:|     ::|.|.|....||...|:..:|.:
Yeast   383 DIGLILEL-----ELTNSGWENIKRI--TTIVLNRLLPSFYVMNIDYLITFLKEQNLIDLVSFLY 440

  Fly   439 Q-----------------------IEPPPI-DHVQSIVESFN-----YLPSKDVL---TGPQLYF 471
            |                       :.||.| ...:|::|..:     |..:|..:   ||..:.|
Yeast   441 QSSEDLPMEECSKLSGILQDDLECLTPPNIFKGFKSLIEIDDPNIEKYENTKANIQWWTGQAIKF 505

  Fly   472 QYEESAIELLRQHMNKFNF------NIMISSYIPYEKNEYDQREPWF------------------ 512
            |      ..|:..||..|.      ||...:.....||:.|....:|
Yeast   506 Q------NFLKSFMNHDNMRLLLLGNIKSGNIFDKMKNKSDICTDFFYEFEYYTANVHLASDNKF 564

  Fly   513 ------------GTQF--KTISMPPKWQTMW------EQSATIKELHYPQP---NPFVTTDFKIH 554
                        |..|  ..:|.|.|.|.::      .:.||::...|.:|   .|.:.::.:.:
Yeast   565 HSNSSYEFNFPTGNLFLPDCVSDPLKLQQLFLECSLKSKFATLRPQIYSEPTRTKPQLVSENQNY 629

  Fly   555 --WVESGKPHVSRSPKALIRNDLCELWFRQDNIFKLPDGYINLYFITPLVRESVKQYMLGVLFTY 617
              |:....|:.:...|:::..::..|..:..     |:..|:|            :.:...||..
Yeast   630 EMWILKEDPNFASDNKSVVSFEVLGLGIKPS-----PEATIHL------------EVLAQALFII 677

  Fly   618 LVEFRMAEQLYPALEAGLTYGLYIGDKG---LVMRVSGYNEKLPLLVEIILNMMQTIELDIGQVN 679
            ...|     |||||..|.||.:....||   |...:||:.|.:..:|:..::.::.|..|...::
Yeast   678 TSSF-----LYPALRIGYTYEIASSSKGNVTLRFTISGFPEGVFTIVKTFVDTLKLIATDPTFLS 737

  Fly   680 AFKD-LKKRQIYNALINGKSLNL--DLRLSILENKRFSMISKY-----ESVDDITMDDIKSFKEN 736
              || |:|.:|   |:..|..|.  |..:.:.......::.||     :.::.:.:.:::|| |.
Yeast   738 --KDTLRKARI---LVRNKYKNASSDNCVKLASVGLLIVLEKYIWTLEDRINALELTELESF-EK 796

  Fly   737 F---------HKKMYVKGLIQ----------GNFTEDQ--ATDLMQKVLDTYKSEKLDNLSALDN 780
            |         |..::::|.::          .|||:..  :.:..:..:..|......:|....|
Yeast   797 FCFLFWRNPKHLVLFMQGSLEYADAINRYLNNNFTQHLKISNEGSKPTIRLYPPPSTKDLDQGTN 861

  Fly   781 HLLQIPLGSYYLRAKTLNEDDSNTIITNYYQIGP-SDLKMECIMDLVELIVEEPFFNQLRTQEQL 844
            ..:     ||     ..::||.|..|..:.|... .|:|...:..|.|.:........||.::|:
Yeast   862 AFI-----SY-----NGHQDDPNNSIVYFIQTAQRDDIKNLTLTFLTEYLFSLTLVPDLRNKKQI 916

  Fly   845 GY-----------SLGIHQRIGYGVLAFLITINTQETKHRADYVEQRIEAFRSRM-AELVSQMSD 897
            ||           ::|||           ||:.:..:.|.   :|.||..:.|.: .:::::.::
Yeast   917 GYIVLGGLRVLTDTVGIH-----------ITVMSGSSGHN---LETRINEYLSYLQLQVLNRFTE 967

  Fly   898 TEFKNI-RETLINGKKLGDTSLDE------EVLRNWSEIVTK-----EYFFNRIE-TQIQMLSHL 949
            .:|:.| .|..:|..|...|...|      ::|   :|||..     .|..|..: .|.:.:.:.
Yeast   968 FDFRRILLEPFLNLLKQNSTKQFEGSAGPVDLL---NEIVANVQNGDNYTLNNKQMRQHRKVRNK 1029

  Fly   950 TKEDVLNFLNDN---DKNNLRKLSVQVVGNHNQTSNSTAQASRSGSLSDLLDDVQDNMANETDSA 1011
            ..|..|||..|:   |.:.|:||:::......::..|...|.|| .||.::             .
Yeast  1030 IAEGRLNFQEDHEMIDISFLQKLTLKKYLAFFESKISIYSAQRS-KLSIMI-------------T 1080

  Fly  1012 KPMTDK 1017
            .||.:|
Yeast  1081 SPMAEK 1086

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	248/1137 (22%)
		Peptidase_M16	85..214	CDD:279066	47/140 (34%)
		Peptidase_M16_C	244..419	CDD:282978	47/223 (21%)
		Peptidase_M16_M	436..720	CDD:292805	72/375 (19%)
		Peptidase_M16_C	724..907	CDD:282978	41/217 (19%)
AXL1	NP_015447.1	Ptr	1..1111	CDD:223956	257/1176 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343064
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S927
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.690