Protein Alignment CG10588 and SDD3

DIOPT Version :10

• Sequence 1: NP_649271.1
• Gene: CG10588 / 40316
• FlyBaseID: FBgn0037037
• Length: 1058
• Species: Drosophila melanogaster
• Sequence 2: NP_014543.1
• Gene: SDD3 / 854055
• SGDID: S000005458
• Length: 1037
• Species: Saccharomyces cerevisiae
• Alignment Length: 1190
• Identity: 228/1190 - (19%)
• Similarity: 410/1190 - (34%)
• Gaps: 384/1190 - (32%)

  Fly    33 VVQYHEEPDKSDGDSKLYRALT--LSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAA 95
            |.|||               :|  :|...:..|:..::...|.:|
Yeast    14 VPQYH---------------ITKYISERTKLQLVHINHKTSPLVH-------------------- 43

  Fly    96 CAVLVGVGSFSEPQQY---QGLAHFVEHMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCF 157
                   |.|:.|.:.   .|..|.:||:|||||:.:|.:...|:....|...:||.|:.::|.:
Yeast    44 -------GYFAVPTECLNDSGAPHTLEHLIFMGSKSYPYKGLLDTAGNLSLSNTNAWTDTDQTVY 101

  Fly   158 YFELDQTHLDRGMDLFMNLMKA-------PLMLPDAMSRE-----------RSAVQSEFEQTHMR 204
                  |....|...|..|:.|       |.:..:|...|           :..|.||.|....:
Yeast   102 ------TLSSAGWKGFSKLLPAYLDHILHPTLTDEACLTEVYHIDPENLGDKGVVFSEMEAIETQ 160

  Fly   205 D------EVRRDQILASLASEGYPHGTFSWGNYKTLKEGVDDSSLHKELHKFYRDHYGSNRMVVA 263
            .      |.:|     .:..||..:.:.:.|..|.|:...:|     |:.:|::..|.|:.:.|.
Yeast   161 GWYISGLEKQR-----LMFPEGSGYRSETGGLTKNLRTLTND-----EIRQFHKSLYSSDNLCVI 215

  Fly   264 LQAQLSLDEL----EE-----------------LLVRHCADIPTSQ----QNSIDVSQLNYQKA- 302
            :...:..|||    ||                 .|....:.||.|:    :::::..:|:..:.
Yeast   216 VCGNVPTDELLTVMEEWDNKLPEIPSNIPKKRPFLDNKLSHIPQSRDKVTESTVEFPELDESQGE 280

  Fly   303 ------------FRDQFYKDVFL---VQPVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIG--Y 350
                        ||:....||.|   ......|...||..:..||.|......|.|:..:|.  .
Yeast   281 LLFSWIGVPYSDFRNDLAVDVLLDYFTDSALAVFTRELVEIDDPMANSTDCCTDYFMRTIIDLRI 345

  Fly   351 EGVGS---------LCAYLRHHLWCISVVAGVAES-------SFDSN--SIYS--LFNICIYLSD 395
            :||.:         :...|:.|...:|.|..|.|:       :::.|  |.:|  :....||.::
Yeast   346 QGVPTEKIAATKTKVLEILKTHTIDLSRVRQVVENTKWEYLLNYEKNGESRFSSAVITDYIYGNE 410

  Fly   396 DGFDHIDEV-----LEATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEPPPIDHVQSIVESF 455
            ||...:..:     .:|...|            |.|:.|.:.|..|        :|:...||.:
Yeast   411 DGSSLVSSLKDLSDFDALLQW------------SQKDWQSLLNRIF--------VDNKPIIVTA- 454

  Fly   456 NYLPSKDVLTGPQLYFQYEESAIELLRQHMNKFN--FNIMISSYIPYEKNEYDQREPWFGTQFKT 518
              .||      ..:|.|.|:...:|::|...:|:  ..:::...:...||..|:..|
Yeast   455 --KPS------ALMYEQLEKEKSDLIKQREAEFDDEKKLVLLKRLNNAKNINDRPIP-------- 503

  Fly   519 ISMPPKWQTMWEQSATIKELHYPQPN---PFVTTDFKIHWVESGKPHVSRSP--KALIRNDLCEL 578
                         .:.:::.....|:   .||.|. .|..|:|.|.:....|  |.::..
Yeast   504 -------------KSLLQKFEIDNPSKSVEFVNTK-SIATVDSYKYNNVSDPLTKKILET----- 549

  Fly   579 WFRQDNIFKL-------PDGYINLYFITPLVRESVKQYMLGVLFTYLVEFRMAEQLY-------- 628
              |.|| |.|       |..:|.|:|:  :...|:|...|      |..|.|.::|:
Yeast   550 --RPDN-FPLFIHLNHFPSQFIELHFL--VNSASIKDTSL------LPYFNMFDELFSMPMKILD 603

  Fly   629 --------------------PALEAGLTYGLYIGDKG---------LVMRVSGYNEKLPLLVEII 664
                                ..::|.:..||    ||         :..|..||:..:..:...:
Yeast   604 EESNVETMLSFEEVVAKLKSETIDAQINQGL----KGSCPDLINFKIQCRAGGYSNSVQWIKHCL 664

  Fly   665 LNMMQTIELDIGQVNAFKDLKKRQIYNALINGKSLNLDLRLSILENKR-FSMISKYESVD----D 724
            .:|:    .|..:|....:    ...|:::..|. |.::.||.|.|:. :|..|..:|.|    :
Yeast   665 FDMV----FDENRVRILLE----NYLNSIVEWKR-NGNVMLSSLTNRNLYSARSLKKSTDPLFVE 720

  Fly   725 ITMDDIKSFKE----NFHKKMY-----VKGLIQGNFTEDQATDL--MQKVLDTYKS--------- 769
            ..:.:|  |.|    ||.|::.     ::..::.||.:.....|  :.|:.|.|:.
Yeast   721 AKLQEI--FAEIENGNFEKEILPRIETMRKQLRANFNKFHILVLGDISKIDDVYEPWNPLIKCLN 783

  Fly   770 -----EK---------LDNLSALDNHLLQIPLGSYYLRAKTLNEDDSNTIITN-----------Y 809
                 ||         ||.:|:    :.:.|....::.....:|.....:||:           |
Yeast   784 IAHPVEKLKIPPVPRALDTISS----ICRTPGEKAFIITTPASESAYMNLITSIPFNLDYHDPEY 844

  Fly   810 YQIGPSDLKMECIMDLVELIVEEPFFNQLRTQEQLGYSLGIHQRIGYGV-LAFLITINTQ--ETK 871
            ..:..:...:||        ||.||:..:|     |..|      .||. :..|..||:.  ...
Yeast   845 AIVSLASEYLEC--------VEGPFWKGIR-----GAGL------AYGASMLKLCEINSWGFNIY 890

  Fly   872 HRADYV------EQRIEAFRSRMAELVSQMSDTEFKNIRETLINGKKLGDTSLDEEVLRNWSEIV 930
            ..||.:      :|.::.:.|...|...|:    .:....::||.....:....|..|..:.:..
Yeast   891 RGADIIKCYEVGKQIVQDYASGALEFDEQL----IQGAISSIINRLATIECGYFETALSKYVDEF 951

  Fly   931 TKEYFFNRIETQIQMLSHLTKEDVLN-----FLNDNDKNNLRKLSVQVVGNHNQTSNSTAQASRS 990
            ..:...|..|..::.|.::||.|:.|     |:|..|.|.    ||..|..|.....|..:...:
Yeast   952 CLQRGNNFNELYLERLQNVTKTDLKNAMQKYFVNMFDSNK----SVAFVSCHPAKLESVQEFFET 1012

  Fly   991 GSLSDLLDDVQDNMANETDS 1010
            ...:..:::::|: .:|.||
Yeast  1013 QGFTVEIEELEDD-DDEIDS 1031

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_649271.1	Ptr	38..996	CDD:440648	220/1169 (19%)
SDD3	NP_014543.1	PqqL	29..458	CDD:440377	98/500 (20%)
		PqqL	<743..996	CDD:440377	53/283 (19%)