DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10588 and AT1G06900

DIOPT Version :9

Sequence 1:	NP_001287135.1	Gene:	CG10588 / 40316	FlyBaseID:	FBgn0037037	Length:	1058	Species:	Drosophila melanogaster
Sequence 2:	NP_172173.2	Gene:	AT1G06900 / 837200	AraportID:	AT1G06900	Length:	1024	Species:	Arabidopsis thaliana

Alignment Length:	1012	Identity:	312/1012 - (30%)
Similarity:	506/1012 - (50%)	Gaps:	89/1012 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KSDGDSKLYRALTLSNGLRAMLISD----------SYIDEPSIHRASRESLNSSTE--------- 87
            ||..|.:|||.:.|.|||.|:||.|          ..|||........:|..||.:
plant    16 KSPNDRRLYRVIELENGLCALLIHDPDIYPEGSVPDQIDEDDEDGEEEDSDGSSEDDDDDEDDEE 80

  Fly    88 --------------------NFNGKLAACAVLVGVGSFSEPQQYQGLAHFVEHMIFMGSEKFPVE 132
                                :...|.||.|:.|.:|||.:|.:.||||||:|||:||||.:||.|
plant    81 DGEGDEEDEDEDEDEVKGKGDHQTKKAAAAMCVSMGSFLDPPEAQGLAHFLEHMLFMGSTEFPDE 145

  Fly   133 NEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMNLMKAPLMLPDAMSRERSAVQSE 197
            ||:||:::|.||.|||:||.|.||::||:.:..|...:..|.....||||..:||.||..||.||
plant   146 NEYDSYLSKHGGSSNAYTEMEHTCYHFEVKREFLQGALKRFSQFFVAPLMKTEAMEREVLAVDSE 210

  Fly   198 FEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTL----KEGVDDSSLHKELHKFYRDHYGSN 258
            |.|....|..|..|:....:::|:|...|:|||.|:|    :.|||   |.:.:.|.|:::|...
plant   211 FNQALQNDACRLQQLQCYTSAKGHPFNRFAWGNKKSLSGAMENGVD---LRECIVKLYKEYYHGG 272

  Fly   259 RMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQKAFRDQFYK--DVFLVQPVEDVC 321
            .|.:.:....|||.||..:|....|:...       |::..........:|  .::.::.|:||.
plant   273 LMKLVVIGGESLDMLESWVVELFGDVKNG-------SKIRPTLEAEGPIWKGGKLYRLEAVKDVH 330

  Fly   322 KLELTWVLPPMKNFYRSKPDMFISQLIGYEGVGSLCAYLRHHLWCISVVAGVAESSFDSNSIYSL 386
            .|:|||.|||:::.|..||:.:::.|:|:||.|||.::|:...|..|:.|||.:...:.:|:..:
plant   331 ILDLTWTLPPLRSAYVKKPEDYLAHLLGHEGRGSLHSFLKAKGWATSLSAGVGDDGINRSSLAYV 395

  Fly   387 FNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEPPPIDHVQSI 451
            |.:.|:|:|.|.:.|.:::...:.::||:.:....:..:||.|.|.|.:|||..|.|..|:...:
plant   396 FGMSIHLTDSGLEKIYDIIGYIYQYLKLLRDVSPQEWIFKELQDIGNMDFRFAEEQPADDYAAEL 460

  Fly   452 VESFNYLPSKDVLTGPQLYFQYEESAIELLRQHMNKFNFNI-MISSYIPYEKNEYDQREPWFGTQ 515
            .|:....|.:.|:.|..:|..::...||.|.......|..| ::|..|   |:|..|:|||||:.
plant   461 SENMLAYPVEHVIYGDYVYQTWDPKLIEDLMGFFTPQNMRIDVVSKSI---KSEEFQQEPWFGSS 522

  Fly   516 FKTISMPPKWQTMWEQSATI-KELHYPQPNPFVTTDFKIHWVESGKPHVSRS-PKALIRNDLCEL 578
            :....:|......|...:.: ..||.|..|.|:..||.|..:.|.....|:| |:.:|.....:.
plant   523 YIEEDVPLSLMESWSNPSEVDNSLHLPSKNQFIPCDFSIRAINSDVDPKSQSPPRCIIDEPFMKF 587

  Fly   579 WFRQDNIFKLPDGYINLYFITPL--VRESVKQYMLGVLFTYLVEFRMAEQLYPALEAGLTYGLYI 641
            |::.|..||:|..  |.||...|  ...|||..:|..|:..|::..:.|.:|.|..|.|...|.:
plant   588 WYKLDETFKVPRA--NTYFRINLKGAYASVKNCLLTELYINLLKDELNEIIYQASIAKLETSLSM 650

  Fly   642 -GDKGLVMRVSGYNEKLPLLVEIILNMMQTIELDIGQVNAFKDLKKRQIYNALINGKSLNLD--L 703
             ||| |.::|.|:|||:|.|:..||.:.::...::.:....|:..:|...|.  |.|.||..  |
plant   651 YGDK-LELKVYGFNEKIPALLSKILAIAKSFMPNLERFKVIKENMERGFRNT--NMKPLNHSTYL 712

  Fly   704 RLSILENKRFSMISKYESVDDITMDDIKSFKENFHKKMYVKGLIQGNFTEDQATDLMQKVLDTYK 768
            ||.:|..:.:....|...::|:::||:.||......:::::.|..||.:||:|.::.....|:..
plant   713 RLQLLCKRIYDSDEKLSVLNDLSLDDLNSFIPELRSQIFIEALCHGNLSEDEAVNISNIFKDSLT 777

  Fly   769 SEKLDNLSALDNHLLQIPLGSYYLR-AKTLNEDDSNTIITNYYQIGPSD---LKMECIMDLVELI 829
            .|.|.:.......:...|:|:..:| ....|:.::|:::..||||.|.:   .:.:.::||...|
plant   778 VEPLPSKCRHGEQITCFPMGAKLVRDVNVKNKSETNSVVELYYQIEPEEAQSTRTKAVLDLFHEI 842

  Fly   830 VEEPFFNQLRTQEQLGYSLGIHQRIGYGVLAFLITINTQETKHRADYVEQRIEAFRSRMAELVSQ 894
            :|||.||||||:|||||.:....|:.|.|..|...:  |.:|:...::..|::.|...:..|:.|
plant   843 IEEPLFNQLRTKEQLGYVVECGPRLTYRVHGFCFCV--QSSKYGPVHLLGRVDNFIKDIEGLLEQ 905

  Fly   895 MSDTEFKNIRETLINGKKLGDTSLDEEVLRNWSEIVTKEYFFNRIETQIQMLSHLTKEDVLN--- 956
            :.|..:::.|..:|......|.||..|....||:||.|.|.|:....:.:.|..:.|:||::
plant   906 LDDESYEDYRSGMIARLLEKDPSLLSETNDLWSQIVDKRYMFDFSHKEAEELRSIQKKDVISWYK 970

  Fly   957 --FLNDNDKNNLRKLSVQVVG-----NHNQTSNSTAQ 986
              |...:.|  .|:|:|:|.|     ...||.....|
plant   971 TYFRESSPK--CRRLAVRVWGCDTNMKETQTDQKAVQ 1005

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	309/1004 (31%)
		Peptidase_M16	85..214	CDD:279066	62/157 (39%)
		Peptidase_M16_C	244..419	CDD:282978	48/176 (27%)
		Peptidase_M16_M	436..720	CDD:292805	87/291 (30%)
		Peptidase_M16_C	724..907	CDD:282978	53/186 (28%)
AT1G06900	NP_172173.2	Ptr	12..969	CDD:223956	302/972 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	124	1.000	Domainoid score	I1811
eggNOG	1	0.900	-	-		E1_COG1025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63000
OrthoDB	1	1.010	-	-		D1008844at2759
OrthoFinder	1	1.000	-	-		FOG0000548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100422
Panther	1	1.100	-	-	O	PTHR43690
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830