DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10588 and AT3G57470

DIOPT Version :9

Sequence 1:	NP_001287135.1	Gene:	CG10588 / 40316	FlyBaseID:	FBgn0037037	Length:	1058	Species:	Drosophila melanogaster
Sequence 2:	NP_001319782.1	Gene:	AT3G57470 / 824914	AraportID:	AT3G57470	Length:	966	Species:	Arabidopsis thaliana

Alignment Length:	1040	Identity:	288/1040 - (27%)
Similarity:	479/1040 - (46%)	Gaps:	134/1040 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DSKLYRALTLSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQ 110
            |.:.||.:.|.|.|..:||||...|:                      .|.::.|.||||::|:.
plant    23 DKREYRRIVLKNSLEVLLISDPETDK----------------------CAASMNVSVGSFTDPEG 65

  Fly   111 YQGLAHFVEHMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMN 175
            .:|||||:|||:|..|||:|.|:.:..::|:.||.:||:|.:|:|.::|:::.......:|.|..
plant    66 LEGLAHFLEHMLFYASEKYPEEDSYSKYITEHGGSTNAYTSSEDTNYHFDINTDSFYEALDRFAQ 130

  Fly   176 LMKAPLMLPDAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTL-----K 235
            ....|||..||..||..||.||.:...:.|..|..|:...|:.|.:|:..||.||..||     :
plant   131 FFIQPLMSTDATMREIKAVDSEHQNNLLSDSWRMAQLQKHLSREDHPYHKFSTGNMDTLHVRPEE 195

  Fly   236 EGVDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQ 300
            .|||..|   ||.|||.:||.:|.|.:.:..:.:||:.:.|:......|..:.|.   :.:...|
plant   196 NGVDTRS---ELIKFYDEHYSANIMHLVVYGKENLDKTQGLVEALFQGIRNTNQG---IPRFPGQ 254

  Fly   301 KAFRDQFYKDVFLVQPVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIGYEGVGSLCAYLRHHLW 365
            ....|.....|..| |:....:|.::|.:.|..:.|...|..::..|||:||.|||...|:...|
plant   255 PCTLDHLQVLVKAV-PIMQGHELSVSWPVTPSISHYEEAPCRYLGDLIGHEGEGSLFHALKILGW 318

  Fly   366 CISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKESQQ 430
            ...:.||.|:.|.:    ||.||:.|.|:|.|.:|:.::|...|.::|::..|...|..:.|...
plant   319 ATGLYAGEADWSME----YSFFNVSIDLTDAGHEHMQDILGLLFEYIKVLQQSGVSQWIFDELSA 379

  Fly   431 IENNNFRFQIEPPPIDHVQSIVESFNYLPSKDVLTGPQLYFQYEESAIELLRQHMNKFNFNIMIS 495
            |....|.:|.:..||.:...|..:....|:|..|.|..|..::..:.::.:...::..|..|.
plant   380 ICEAEFHYQAKIDPISYAVDISSNMKIYPTKHWLVGSSLPSKFNPAIVQKVLDELSPNNVRIF-- 442

  Fly   496 SYIPYEKNEY----DQREPWFGTQFKTISMPPKWQTMWEQSATIKELHYPQPNPFVTTDFKIHWV 556
                :|.|::    |:.|||:.|.:....:.......|.|||....|..|.||.|:.|||.:..:
plant   443 ----WESNKFEGQTDKVEPWYNTAYSLEKITKFTIQEWMQSAPDVNLLLPTPNVFIPTDFSLKDL 503

  Fly   557 ESGKPHVSRSPKALIRNDLCELWFRQDNIFKLPDGYINLYFITPLVRESVKQYMLGVLFTYLVEF 621
            :.    ....|..|.:.....||::.|..|..|..|:.:.|..||...|....:|..:|.:|:..
plant   504 KD----KDIFPVLLRKTSYSRLWYKPDTKFFKPKAYVKMDFNCPLAVSSPDAAVLSDIFVWLLVD 564

  Fly   622 RMAEQLYPALEAGLTYGLYIGDKGLVMRVSGYNEKLPLLVEIILNMMQTIELDIGQ--------V 678
            .:.|..|.|..|||.|||.:.|.|..:.::|:|.||.:|:|.::..:...|:...:        .
plant   565 YLNEYAYYAQAAGLDYGLSLSDNGFELSLAGFNHKLRILLEAVIQKIAKFEVKPDRFSVIKETVT 629

  Fly   679 NAFKDLKKRQIYNALINGKSLNLDLRLSILENKRFSMISKYESVDDITMDDIKSFKENFHKKMYV 743
            .|:::.|.:|.:....|..||       :|:::.:....:.:::..:..:|:.:|......:.:|
plant   630 KAYQNNKFQQPHEQATNYCSL-------VLQDQIWPWTEELDALSHLEAEDLANFVPMLLSRTFV 687

  Fly   744 KGLIQGNFTEDQATDLMQKVLDTYKSEK------LDNLSALDNHLLQIPLGS---YYLRAKTLNE 799
            :..|.||..:|:|..:::.:.|...::.      |.....|.|.:.::..|.   ||....  |.
plant   688 ECYIAGNVEKDEAESMVKHIEDVLFTDSKPICRPLFPSQFLTNRVTELGTGMKHFYYQEGS--NS 750

  Fly   800 DDSNTIITNYYQIGPSDLKMECIMDLVELIVEEPFFNQLRTQEQLGY--SLGIHQRIG-YGVLAF 861
            .|.|:.:.:|.|:...:..|...:.|.|||.::..|:||||.|||||  ||.:....| ||| .|
plant   751 SDENSALVHYIQVHKDEFSMNSKLQLFELIAKQDTFHQLRTIEQLGYITSLSLSNDSGVYGV-QF 814

  Fly   862 LITINTQETKHRADYVEQRIEAFRSRMAELVSQMSDTEFKNIRETLINGKKLGDTSLDEEVLRNW 926
            :|..:.:...|    ::.|:|:....:......|||.|||:....||:.|...|.:||||....|
plant   815 IIQSSVKGPGH----IDSRVESLLKDLESKFYNMSDEEFKSNVTNLIDMKLEKDKNLDEESWFYW 875

  Fly   927 SEIVTKEYFFNRIETQIQMLSHLTKEDVLNFLNDN---DKNNLRKLSVQVVGNHNQTSNSTAQAS 988
            :||.|....||||:.::..|..|.|::.::|.::.   |..|.:.||:.|.||.:
plant   876 AEIQTGTLKFNRIDAEVAALRLLKKDEWIDFFDEYIKVDAPNKKSLSICVYGNQH---------- 930

  Fly   989 RSGSLSDLLDDVQDNMANETDSAKPMTDKIRLEFLGESDDPSS---IKDIYAFKKDLYVFPLFNT 1050
                |.::.:|               .|||          ||:   |:||..|:|..   ||:.:
plant   931 ----LKEMRND---------------KDKI----------PSTSIEIEDIVCFRKSQ---PLYGS 963

Fly 1051 1050
plant 964 963

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	274/965 (28%)
		Peptidase_M16	85..214	CDD:279066	46/128 (36%)
		Peptidase_M16_C	244..419	CDD:282978	50/174 (29%)
		Peptidase_M16_M	436..720	CDD:292805	71/295 (24%)
		Peptidase_M16_C	724..907	CDD:282978	52/194 (27%)
AT3G57470	NP_001319782.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1025
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63000
OrthoDB	1	1.010	-	-		D1008844at2759
OrthoFinder	1	1.000	-	-		FOG0000548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100422
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730