DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10588 and AT2G41790

DIOPT Version :9

Sequence 1:	NP_001287135.1	Gene:	CG10588 / 40316	FlyBaseID:	FBgn0037037	Length:	1058	Species:	Drosophila melanogaster
Sequence 2:	NP_181710.1	Gene:	AT2G41790 / 818778	AraportID:	AT2G41790	Length:	970	Species:	Arabidopsis thaliana

Alignment Length:	1023	Identity:	287/1023 - (28%)
Similarity:	479/1023 - (46%)	Gaps:	117/1023 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 DSKLYRALTLSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQ 110
            |::.||.:.|.|.|:.:||||...|:                      .|.::.|.|||||:||.
plant    21 DNREYRMIVLKNLLQVLLISDPDTDK----------------------CAASMSVSVGSFSDPQG 63

  Fly   111 YQGLAHFVEHMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMN 175
            .:|||||:|||:|..|||:|.|:.:..::|:.||.:||:|.:|||.::|:::....|..:|.|..
plant    64 LEGLAHFLEHMLFYASEKYPEEDSYSKYITEHGGSTNAYTASEETNYHFDVNADCFDEALDRFAQ 128

  Fly   176 LMKAPLMLPDAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTL-----K 235
            ....|||..||..||..||.||.::..:.|..|..|:...|:.|.:|:..||.||..||     .
plant   129 FFIKPLMSADATMREIKAVDSENQKNLLSDGWRIRQLQKHLSKEDHPYHKFSTGNMDTLHVRPQA 193

  Fly   236 EGVDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQ 300
            :|||..|   ||.|||.:||.:|.|.:.:..:.|||::::|:.|...:|   |..:..|.:...|
plant   194 KGVDTRS---ELIKFYEEHYSANIMHLVVYGKESLDKIQDLVERMFQEI---QNTNKVVPRFPGQ 252

  Fly   301 KAFRDQFYKDVFLVQ--PVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIGYEGVGSLCAYLRHH 363
            ....|...   .||:  |::...||.::|.:.|..:.|...|..::..|||:||.|||...|:..
plant   253 PCTADHLQ---ILVKAIPIKQGHKLGVSWPVTPSIHHYDEAPSQYLGHLIGHEGEGSLFHALKTL 314

  Fly   364 LWCISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKES 428
            .|...:.||..|.:.|    ||.|.:.|.|:|.|.:|:.|:|...|.:::|:..:...|..:.|.
plant   315 GWATGLSAGEGEWTLD----YSFFKVSIDLTDAGHEHMQEILGLLFNYIQLLQQTGVCQWIFDEL 375

  Fly   429 QQIENNNFRFQIEPPPIDHVQSIVESFNYLPSKDVLTGPQLYFQYEESAIELLRQHMNKFNFNIM 493
            ..|....|.:|.:.||:.::..|..:....|:||.|.|..|..::..:.::.:...::..||.|.
plant   376 SAICETKFHYQDKIPPMSYIVDIASNMQIYPTKDWLVGSSLPTKFNPAIVQKVVDELSPSNFRIF 440

  Fly   494 ISSYIPYEKNEYDQREPWFGTQFKTISMPPKWQTMWEQSATIKELHYPQPNPFVTTDFKIHWVES 558
            ..|. .:| .:.|:.|||:.|.:....:.......|.|||....||.|.||.|:.||..:...:.
plant   441 WESQ-KFE-GQTDKAEPWYNTAYSLEKITSSTIQEWVQSAPDVHLHLPAPNVFIPTDLSLKDADD 503

  Fly   559 GKPHVSRSPKALIRNDLCELWFRQDNIFKLPDGYINLYFITPLVRESVKQYMLGVLFTYLVEFRM 623
             |..|   |..|.:.....||::.|.:|..|..|:.:.|..||...|....:|..:||.|:...:
plant   504 -KETV---PVLLRKTPFSRLWYKPDTMFSKPKAYVKMDFNCPLAVSSPDAAVLTDIFTRLLMDYL 564

  Fly   624 AEQLYPALEAGLTYGLYIGDKGLVMRVSGYNEKLPLLVEIILNMMQTIELDIGQ--------VNA 680
            .|..|.|..|||.||:.:.|.|..:.:.|||.||.:|:|.::..:...|:...:        ...
plant   565 NEYAYYAQVAGLYYGVSLSDNGFELTLLGYNHKLRILLETVVGKIANFEVKPDRFAVIKETVTKE 629

  Fly   681 FKDLKKRQIYNALINGKSLNLDLRLSILENKRFSMISKYESVDDITMDDIKSFKENFHKKMYVKG 745
            :::.|.||.|:..:...||       ||:::.:....:.:.:..:..:|:..|......:.:::.
plant   630 YQNYKFRQPYHQAMYYCSL-------ILQDQTWPWTEELDVLSHLEAEDVAKFVPMLLSRTFIEC 687

  Fly   746 LIQGNFTEDQATDLMQKVLDTYKSE------KLDNLSALDNHLLQIPLG-SYYLRAKTLNEDDSN 803
            .|.||...::|..:::.:.|...::      .|.....|.|.::::..| .|:......|..|.|
plant   688 YIAGNVENNEAESMVKHIEDVLFNDPKPICRPLFPSQHLTNRVVKLGEGMKYFYHQDGSNPSDEN 752

  Fly   804 TIITNYYQIGPSDLKMECIMDLVELIVEEPFFNQLRTQEQLGYSLGIHQRIGYGV--LAFLITIN 866
            :.:.:|.|:...|..|...:.|..|:.::..|:||||.|||||...:.||...|:  :.|:|..:
plant   753 SALVHYIQVHRDDFSMNIKLQLFGLVAKQATFHQLRTVEQLGYITALAQRNDSGIYGVQFIIQSS 817

  Fly   867 TQETKHRADYVEQRIEAFRSRMAELVSQMSDTEFKNIRETLINGKKLGDTSLDEEVLRNWSEIVT 931
            .:...|....||..::.|.|::.|    ||:.:||:....||:.|.....:|.||....|.||.:
plant   818 VKGPGHIDSRVESLLKNFESKLYE----MSNEDFKSNVTALIDMKLEKHKNLKEESRFYWREIQS 878

  Fly   932 KEYFFNRIETQIQMLSHLTKEDVLNFLNDNDK---NNLRKLSVQVVGNHNQTSNSTAQASRSGSL 993
            ....|||.|.::..|..|.|:::::|.::..|   ...:.||::|.|:.:
plant   879 GTLKFNRKEAEVSALKQLQKQELIDFFDEYIKVGAARKKSLSIRVYGSQH--------------- 928

  Fly   994 SDLLDDVQDNMANETDSAKPMTDKIRLEFLGESDDPS-SIKDIYAFKK 1040
                   ...||::.|               |...|| .|:||..|:|
plant   929 -------LKEMASDKD---------------EVPSPSVEIEDIVGFRK 954

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	276/960 (29%)
		Peptidase_M16	85..214	CDD:279066	50/128 (39%)
		Peptidase_M16_C	244..419	CDD:282978	54/176 (31%)
		Peptidase_M16_M	436..720	CDD:292805	77/291 (26%)
		Peptidase_M16_C	724..907	CDD:282978	46/191 (24%)
AT2G41790	NP_181710.1	Ptr	15..944	CDD:223956	281/1011 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1025
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63000
OrthoDB	1	1.010	-	-		D1008844at2759
OrthoFinder	1	1.000	-	-		FOG0000548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100422
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730