DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10588 and UQCR-C1

DIOPT Version :9

Sequence 1:	NP_001287135.1	Gene:	CG10588 / 40316	FlyBaseID:	FBgn0037037	Length:	1058	Species:	Drosophila melanogaster
Sequence 2:	NP_650401.1	Gene:	UQCR-C1 / 41800	FlyBaseID:	FBgn0038271	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	84/381 - (22%)
Similarity:	154/381 - (40%)	Gaps:	78/381 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQYQGLAHFVE 119
            |.||||.                       ::|:.....|...:.:..||.||.::..|:|||:|
  Fly    46 LDNGLRV-----------------------ASEDSGASTATVGLWIDAGSRSENEKNNGVAHFLE 87

  Fly   120 HMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMNLMKAPLMLP 184
            ||.|.|:.| ..:.:.:..|...|...||:|..|:|.||.:.....:.:.:::..::::...:..
  Fly    88 HMAFKGTAK-RSQTDLELEVENLGAHLNAYTSREQTVFYAKCLSKDVPKAVEILADIIQNSKLGE 151

  Fly   185 DAMSRERSAVQSEFEQTHMR-DEVRRDQILASLASEGYPHGTFSWGNYKTLKEGVDDSSLHK-EL 247
            ..::||||.:..|.::.... .||..|.:.|: |.:|.|.|....|..|.::      |:.| :|
  Fly   152 AEIARERSVILREMQEVESNLQEVVFDHLHAT-AYQGTPLGQTILGPTKNIQ------SIGKADL 209

  Fly   248 HKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSI--DVSQLNY---QKAFRDQF 307
            ..:.:.||.::|:|:|....:..|:|.:|.   |:.:...:.:.:  :|:...:   :...||..
  Fly   210 TDYIQTHYKASRIVLAAAGGVKHDDLVKLA---CSSLGGLEASVLPAEVTPCRFTGSEVRVRDDS 271

  Fly   308 YKDVFLVQPVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIG----YEGVGSLCAYLRHHLWCIS 368
            .....:...||. |    .|.  ...|.    |.|..:.|:|    .:|.|:            :
  Fly   272 LPLAHVAIAVEG-C----GWT--DQDNI----PLMVANTLVGAWDRSQGGGA------------N 313

  Fly   369 VVAGVAESSFDSNSIYSL--FNIC--------IYLSDDGFDHIDEVLEATFAWVKL 414
            ..:.:|.:|.:.|..:|.  ||.|        ||...|.....|.:......|::|
  Fly   314 NASNLARASAEDNLCHSFQSFNTCYKDTGLWGIYFVCDPLQCEDMLFNVQTEWMRL 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10588	NP_001287135.1	Ptr	27..980	CDD:223956	84/381 (22%)
		Peptidase_M16	85..214	CDD:279066	33/129 (26%)
		Peptidase_M16_C	244..419	CDD:282978	38/191 (20%)
		Peptidase_M16_M	436..720	CDD:292805
		Peptidase_M16_C	724..907	CDD:282978
UQCR-C1	NP_650401.1	PqqL	35..459	CDD:223685	84/381 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445069
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840