Protein Alignment Sems and PRTN3

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_002768.3
• Gene: PRTN3 / 5657
• HGNCID: 9495
• Length: 256
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 72/273 - (26%)
• Similarity: 110/273 - (40%)
• Gaps: 60/273 - (21%)

  Fly    31 LAKIVLPPAYQTRVIGGRVTTNAKLGGYLVAMRYFNN---FICGGTLIHELIVLTAAHCFEDRAE 92
            ||.::...|....::||. ........|:.:::...|   ..|||||||...|||||||..|..:
Human    15 LALLLSGAARAAEIVGGH-EAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQ 78

  Fly    93 KEAWSVDGGISRLSEKGIRRQ--VKRFIKSAQFKMVTMN--------MDVAVVLLNRPM-VGKNI 146
            :....|      |....:|.|  .::....||   |.:|        .||.::.|:.|. :..::
Human    79 RLVNVV------LGAHNVRTQEPTQQHFSVAQ---VFLNNYDAENKLNDVLLIQLSSPANLSASV 134

  Fly   147 GTLSLCSTALTPGQTMDV--------SGWGMTNPDDEGPGHMLRTVSVPVI-----EKRICREAY 198
            .|:.|      |.|...|        .|||.....|. |..:|:.::|.|:     ...||....
Human   135 ATVQL------PQQDQPVPHGTQCLAMGWGRVGAHDP-PAQVLQELNVTVVTFFCRPHNICTFVP 192

  Fly   199 RESVSISDSMFCASVLGKKDACTYDSGGPLVYEKQVCGIVSFGI-GCASRRYPGVYTDVHYVKPF 262
            |....|               |..||||||:.:..:.||.||.| |||:|.:|..:|.|.....:
Human   193 RRKAGI---------------CFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDW 242

  Fly   263 IVKGIKALLSRSR 275
            |...::.:.::.|
Human   243 IRSTLRRVEAKGR 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	67/247 (27%)
PRTN3	NP_002768.3	Tryp_SPc	28..246	CDD:238113	68/249 (27%)