Protein Alignment Sems and KLK10

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_002767.2
• Gene: KLK10 / 5655
• HGNCID: 6358
• Length: 276
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 73/253 - (28%)
• Similarity: 114/253 - (45%)
• Gaps: 23/253 - (9%)

  Fly    32 AKIVLPPAYQTRVIGGRVTTNAKLGGYLVAMRYFN--NFICGGTLIHELIVLTAAHCFEDRAEKE 94
            |:..|.|...||:......:....|.....:..||  :|.|.|.|:.:..|||||||    ..|.
Human    31 AEAALLPQNDTRLDPEAYGSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHC----GNKP 91

  Fly    95 AWSVDGGISRLSEKGIRRQVKRFIKSAQFKMV-----------TMNMDVAVVLLNRPMV-GKNIG 147
            .|:..|....|..:|  .|::|..:|......           |...|:.::.|.||:| |..:.
Human    92 LWARVGDDHLLLLQG--EQLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVR 154

  Fly   148 TLSLCSTALTPGQTMDVSGWGMTNPDDEGPGHMLRTVSVPVIEKRICREAYRESVSISDSMFCAS 212
            .|.|......||....|:|||.|..........|...|:.::..:.| |.:...| ::::|.||.
Human   155 ALQLPYRCAQPGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKEC-EVFYPGV-VTNNMICAG 217

  Fly   213 VLGKKDACTYDSGGPLVYEKQVCGIVSFGI-GCASRRYPGVYTDVHYVKPFIVKGIKA 269
            :...:|.|..|||||||.::.:.||:|:|: .|.|.::|.|||.:.....:|.|.|::
Human   218 LDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	66/234 (28%)
KLK10	NP_002767.2	Tryp_SPc	49..272	CDD:238113	66/230 (29%)