DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sems and Prss53

DIOPT Version :9

Sequence 1:	NP_649270.1	Gene:	Sems / 40315	FlyBaseID:	FBgn0037036	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_001074737.1	Gene:	Prss53 / 330657	MGIID:	2652890	Length:	552	Species:	Mus musculus

Alignment Length:	211	Identity:	63/211 - (29%)
Similarity:	91/211 - (43%)	Gaps:	37/211 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 MRYFNNFICGGTLIHELIVLTAAHCFEDRAEKEAWSVDGGISRLSEKGIRRQVKRFIKSAQFKMV 126
            :::.....|||.|:.|::||||||||..|...|.|||..|... .|.|:    |:.|....:...
Mouse   318 LKHHGKLACGGALVSEVVVLTAAHCFIGRQTLEEWSVGLGAGP-EEWGL----KQLILHGAYTHP 377

  Fly   127 TMNMDVAVVLLNRPM-VGKNIGTLSL--CSTALTPGQTMDVSGW--------GMTNPDDEGPGHM 180
            ....|||.:||.:|: :|..:..|.|  ....|..|:    .||        |:..|
Mouse   378 EGGYDVAFLLLAQPVTLGPGLRPLCLPYADHHLPDGE----HGWVLGLTQKAGINYP-------- 430

  Fly   181 LRTVSVPVIEKRICREAYR----ESVSISDSMFCASVLGKKDACTYDSGGPLVYEKQ----VCGI 237
             :||.|.|:....|...:.    ..:.|...|.|.:|:|:...|...||.|||:|.:    :.|:
Mouse   431 -QTVPVTVLGPMACSRQHAAPGGTGIPILPGMVCTTVVGEPPHCEGLSGAPLVHEIRGTWFLVGL 494

  Fly   238 VSFGIGCASRRYPGVY 253
            .|||..|.|...|.|:
Mouse   495 HSFGDTCQSSAKPAVF 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	63/211 (30%)
Sems	NP_649270.1	Tryp_SPc	44..265	CDD:238113	63/211 (30%)
Prss53	NP_001074737.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..46
		Tryp_SPc	45..271	CDD:238113
		Tryp_SPc	311..522	CDD:238113	63/211 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100