Protein Alignment Sems and C1r

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_001128027.1
• Gene: C1r / 312705
• RGDID: 1309091
• Length: 707
• Species: Rattus norvegicus
• Alignment Length: 263
• Identity: 73/263 - (27%)
• Similarity: 112/263 - (42%)
• Gaps: 55/263 - (20%)

  Fly    33 KIVLPPAYQTRVIGGRVTTNAKLGGYLVAMRYFNNF--ICGGTLIHELIVLTAAHCFEDR----- 90
            |.|.|...:.|:|||:   .|..|.:  ..:.|.|.  ..||.|:.:..:|||||....:
  Rat   453 KPVNPVTQKQRIIGGQ---KANPGNF--PWQAFTNIHGRGGGALLGDRWILTAAHTIYPKEHNKE 512

  Fly    91 ----AEKEAWSVDGGISRLSEKGIRRQVKRFIKSAQFKMVTMNM---DVAVV-LLNRPMVGKNIG 147
                ..|:.:.....:..:.:.| ...|:|.|....::....|.   |:|:: |.|...:|.|:
  Rat   513 NNVNVSKDVFLGHTNVEEIKKLG-HHPVRRVIIHPDYRQDEPNNFEGDIALLELENSVTLGPNL- 575

  Fly   148 TLSLCSTALTPGQTM-------DVSGWGMTNPDDEGPGHMLRTVSVPVIEKRICREAYRESVS-- 203
             |.:|   |...:|.       .|||:|:|   ::.....||.|.:|:.::..|:...|...|
  Rat   576 -LPIC---LPDNETFYDKDLMGYVSGFGIT---EDKIAFNLRFVRLPIADREACQRWLRTKNSND 633

  Fly   204 -ISDSMFCASVLG----KKDACTYDSGGPLVYEKQ------VCGIVSFGIGCASRRYPGVYTD-V 256
             .|.:|||:   |    |.|||..||||......:      ..||||:||||....  |.||. :
  Rat   634 VFSQNMFCS---GDPTLKHDACQGDSGGVFAVRDRSRDIWVATGIVSWGIGCGEGY--GFYTKLL 693

  Fly   257 HYV 259
            :||
  Rat   694 NYV 696

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	70/253 (28%)
C1r	NP_001128027.1	CUB	27..138	CDD:214483
		FXa_inhibition	161..189	CDD:464251
		CUB	195..302	CDD:395345
		Sushi	309..371	CDD:459664
		CCP	376..447	CDD:153056
		Tryp_SPc	463..699	CDD:214473	70/253 (28%)