Protein Alignment Sems and GZMA

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_006135.2
• Gene: GZMA / 3001
• HGNCID: 4708
• Length: 262
• Species: Homo sapiens
• Alignment Length: 231
• Identity: 70/231 - (30%)
• Similarity: 114/231 - (49%)
• Gaps: 17/231 - (7%)

  Fly    34 IVLPPAYQTRVIGG-RVTTNAKLGGYLVAMRYFNNFICGGTLIHELIVLTAAHCFEDRAEKEAWS 97
            :::|.....::||| .||.:::  .|:|.:......||.|.||.:..|||||||   ...|.:..
Human    19 LLIPEDVCEKIIGGNEVTPHSR--PYMVLLSLDRKTICAGALIAKDWVLTAAHC---NLNKRSQV 78

  Fly    98 VDGGISRLSEKGIRR--QVKRFIKSAQFKMVTMNMDVAVV-LLNRPMVGKNIGTLSLCSTA--LT 157
            :.|..|...|:..::  .||:......:...|...|:.:: |:.:..:.|.:..|.|....  :.
Human    79 ILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLMEKAKINKYVTILHLPKKGDDVK 143

  Fly   158 PGQTMDVSGWGMTNPDDEGPGHMLRTVSVPVIEKRIC--REAYRESVSISDSMFCA-SVLGKKDA 219
            ||....|:|||.|: :.......||.|::.:|::::|  |..|..:..|..:|.|| |:.|.:|:
Human   144 PGTMCQVAGWGRTH-NSASWSDTLREVNITIIDRKVCNDRNHYNFNPVIGMNMVCAGSLRGGRDS 207

  Fly   220 CTYDSGGPLVYEKQVCGIVSFGI--GCASRRYPGVY 253
            |..|||.||:.|....|:.|||:  .|...|.||||
Human   208 CNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVY 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	69/222 (31%)
GZMA	NP_006135.2	Tryp_SPc	29..254	CDD:238113	69/221 (31%)