DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sems and Sp212

DIOPT Version :9

Sequence 1:	NP_649270.1	Gene:	Sems / 40315	FlyBaseID:	FBgn0037036	Length:	275	Species:	Drosophila melanogaster
Sequence 2:	NP_996209.2	Gene:	Sp212 / 2768666	FlyBaseID:	FBgn0053329	Length:	516	Species:	Drosophila melanogaster

Alignment Length:	196	Identity:	52/196 - (26%)
Similarity:	86/196 - (43%)	Gaps:	36/196 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 FICGGTLIHELIVLTAAHCF----EDRAEKEAWSVDGGISR-----LSEKGIR-RQVKRFIKSAQ 122
            |.|.|:||...||::||||.    |||       |..|:.|     ..|.|.. |.|.|.:....
  Fly   304 FKCRGSLISSSIVISAAHCVHRMTEDR-------VVVGLGRYDLDDYGEDGAEMRNVMRLLWHPD 361

  Fly   123 FKMVT-MNMDVAVVLLNRPMVGKNIGTLSLCSTALTPGQTMD----VSGWGMTNPDDEGPGHMLR 182
            :...: .:.|:|::.:.||:...:| ...:|...:...:|:.    ::|||  ..:|.......|
  Fly   362 YNTRSYSDADIALITIERPVTFNDI-IAPICMWTVEASRTVSTTGFIAGWG--RDEDSSRTQYPR 423

  Fly   183 TVSVPVIEKRICREAYRESVSISDSMFCASVLGKKDA---CTYDSGGPLVYEK----QVCGIVSF 240
            .|...:....:|...:|.:: :::...||   |.:|.   |..||||.|:.::    .:.||||.
  Fly   424 VVEAEIASPTVCASTWRGTM-VTERSLCA---GNRDGSGPCVGDSGGGLMVKQGDRWLLRGIVSA 484

  Fly   241 G 241
            |
  Fly   485 G 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	52/196 (27%)
Sems	NP_649270.1	Tryp_SPc	44..265	CDD:238113	52/196 (27%)
Sp212	NP_996209.2	GD_N	23..122	CDD:292649
		Tryp_SPc	277..514	CDD:238113	52/196 (27%)
		Tryp_SPc	277..511	CDD:214473	52/196 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I3868
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.050