Protein Alignment Sems and PRSS55

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: XP_047277448.1
• Gene: PRSS55 / 203074
• HGNCID: 30824
• Length: 376
• Species: Homo sapiens
• Alignment Length: 233
• Identity: 69/233 - (29%)
• Similarity: 117/233 - (50%)
• Gaps: 23/233 - (9%)

  Fly    42 TRVIGGRVTTNAKLGGY--LVAMRYFNNFICGGTLIHELIVLTAAHC-FEDRAEKEAWSVDGGIS 103
            :|:.||   ..|::|.:  .|:::..:...|||:::::..:|||||| :.:....|..||..|.:
Human    90 SRITGG---MEAEVGEFPWQVSIQARSEPFCGGSILNKWWILTAAHCLYSEELFPEELSVVLGTN 151

  Fly   104 RLSEKGIR-RQVKRFIKSAQFKMVTMNMDVAVVLLNRPMVGKNIGTLSLCSTALTPGQTMD--VS 165
            .|:...:. ::|...|....||...|:.|:|::||..|:...::.......|...|....:  |:
Human   152 DLTSPSMEIKEVASIILHKDFKRANMDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRECWVA 216

  Fly   166 GWGMTNPDDEGPGHM-LRTVSVPVIEKRICREAYRESVSISDSMFCASVLGKK-DACTYDSGGPL 228
            |||.||..|:..... |....:.:::...|.:.:.:   ::.:|.||....:. |||..||||||
Human   217 GWGQTNAADKNSVKTDLMKAPMVIMDWEECSKMFPK---LTKNMLCAGYKNESYDACKGDSGGPL 278

  Fly   229 VY-----EK--QVCGIVSFGIGCASRRYPGVYTD-VHY 258
            |.     ||  || ||:|:|..|..:..||:||. |:|
Human   279 VCTPEPGEKWYQV-GIISWGKSCGEKNTPGIYTSLVNY 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	69/232 (30%)
PRSS55	XP_047277448.1	Tryp_SPc	92..322	CDD:238113	68/231 (29%)