Protein Alignment Sems and Gzmk

DIOPT Version :10

• Sequence 1: NP_649270.1
• Gene: Sems / 40315
• FlyBaseID: FBgn0037036
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_032222.1
• Gene: Gzmk / 14945
• MGIID: 1298232
• Length: 263
• Species: Mus musculus
• Alignment Length: 287
• Identity: 84/287 - (29%)
• Similarity: 133/287 - (46%)
• Gaps: 56/287 - (19%)

  Fly     9 LLAGILINNHALQHNETIDLKKLAKIVLPPAYQTRVIGGR-VTTNAKLGGYLVAMRYFNNFICGG 72
            |:||:.:::.                    .:.|.:|||| |..:::  .::.:::|.:..||||
Mouse    11 LVAGVYMSSE--------------------CFHTEIIGGREVQPHSR--PFMASIQYRSKHICGG 53

  Fly    73 TLIHELIVLTAAHCFEDRAEKEAWSVDG-------GISRLSEKGIRRQ---VKRFIKSAQFKMVT 127
            .|||...|||||||:       :|...|       |...||:....:|   :|:||..::.:..:
Mouse    54 VLIHPQWVLTAAHCY-------SWFPRGHSPTVVLGAHSLSKNEPMKQTFEIKKFIPFSRLQSGS 111

  Fly   128 MNMDVAVVLLNRPM-VGKNIGTLSLCS-TALTPGQTMDVSGWGMTNPDDEGPGHMLRTVSVPVIE 190
            .:.|:.::.|.... :.||:..|.|.| ..|..|....|:|||.|.||.......||.|:|.:|.
Mouse   112 ASHDIMLIKLRTAAELNKNVQLLHLGSKNYLRDGTKCQVTGWGTTKPDLLTASDTLREVTVTIIS 176

  Fly   191 KRIC--REAYRESVSISDSMFCA-SVLGKKDACTYDSGGPLVYEKQVCGIVSFGIGCASRRYPGV 252
            ::.|  :..|.....|:..|.|| ...|:||:|..||||||:.:.....:||.|..|...:.||:
Mouse   177 RKRCNSQSYYNHKPVITKDMICAGDARGQKDSCKGDSGGPLICKGIFHALVSQGYKCGIAKKPGI 241

  Fly   253 YTDVHYVKPFIVK----GIKALLSRSR 275
            ||       .:.|    .||:.|:.||
Mouse   242 YT-------LLTKKYQTWIKSKLAPSR 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sems	NP_649270.1	Tryp_SPc	43..263	CDD:214473	74/235 (31%)
Gzmk	NP_032222.1	Tryp_SPc	26..256	CDD:238113	77/245 (31%)