DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fng and Rfng

DIOPT Version :9

Sequence 1:	NP_524191.1	Gene:	fng / 40314	FlyBaseID:	FBgn0011591	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	XP_008766703.1	Gene:	Rfng / 60433	RGDID:	621322	Length:	353	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	155/419 - (36%)
Similarity:	201/419 - (47%)	Gaps:	98/419 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RFKRILQAMMLAVAVVYMTLLLYQSAYGYPGIQVPHSQVDALASEAVTTHRDQLLQDYVQSSTPT 76
            |.:|:|....||:|.|...|||.......| :.:|.
  Rat     3 RVRRVLCRACLALAAVLAVLLLLPLPLPLP-LPLPR----------------------------- 37

  Fly    77 QPGAGAPAASPTTVIIRKDIRSFNFSDIEVSERPTATLLTELARRSRNGELLRDLSQRAVTATPQ 141
                 |||..|..|                   ||.:|..|::|.                   |
  Rat    38 -----APAPDPGRV-------------------PTGSLTLEVSRL-------------------Q 59

  Fly   142 PPVTELDDIFISVKTTKNYHDTRLALIIKTWFQLARDQTWFFTDTDDHYYQEKTKGHLINTKCSQ 206
            |     ||:||:||||:..|..||.|:::||...|..||:.|||.||...|......:|||.||.
  Rat    60 P-----DDVFIAVKTTRKNHGPRLRLLLRTWISRAPRQTFIFTDGDDPELQLLAGSQMINTNCSA 119

  Fly   207 GHFRKALCCKMSAELDVFLESGKKWFCHFDDDNYVNVPRLVKLLDEYSPSVDWYLGKPSISSPLE 271
            ...|:|||||||.|.|.|:|||:|||||.|||||||...|:.||..:|.:.|.|||:||:..|:|
  Rat   120 VRTRQALCCKMSVEYDKFIESGRKWFCHVDDDNYVNPKSLLHLLSTFSSNQDIYLGRPSLDHPIE 184

  Fly   272 IHLDSKNTTTNKKITFWFATGGAGFCLSRALTLKMLPIAGGGKFISIGDKIRFPDDVTMGFIIEH 336
            .....:...|:..:.||||||||||||||.|.|||.|.|..|.|:|..:::|.|||.|:|:|:|.
  Rat   185 ATERVQGGGTSNTVKFWFATGGAGFCLSRGLALKMSPWASLGSFMSTAERVRLPDDCTVGYIVEG 249

  Fly   337 LLKVPLTVVDNFHSHLEPMEFI---------------RQD----TFQDQVSFSYAHMKNQWNVIK 382
            ||...|.....||||||.::.:               |.|    .|..||:.||...:|..||:.
  Rat   250 LLGARLLHSPLFHSHLENLQKLPSGAVLQQQVEDPGGRTDPHPPRFPSQVTLSYGGPENPHNVVN 314

  Fly   383 VDG-FDMKTDPKRFYSLHCQLFPYFSFCP 410
            |.| |.::.||.||.|:||.|:|...:||
  Rat   315 VAGSFSIRQDPTRFQSVHCLLYPDTHWCP 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fng	NP_524191.1	Fringe	145..394	CDD:190308	122/268 (46%)
Rfng	XP_008766703.1	Fringe	58..327	CDD:190308	124/292 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348984
Domainoid	1	1.000	238	1.000	Domainoid score	I2221
eggNOG	1	0.900	-	-		E1_2C9I6
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56433
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3016
OMA	1	1.010	-	-		QHG47481
OrthoDB	1	1.010	-	-		D356445at33208
OrthoFinder	1	1.000	-	-		FOG0002392
OrthoInspector	1	1.000	-	-		otm46033
orthoMCL	1	0.900	-	-		OOG6_104952
Panther	1	1.100	-	-	LDO	PTHR10811
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1586
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810