DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fng and Mfng

DIOPT Version :9

Sequence 1:	NP_524191.1	Gene:	fng / 40314	FlyBaseID:	FBgn0011591	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_954541.1	Gene:	Mfng / 315119	RGDID:	735126	Length:	321	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	134/289 - (46%)
Similarity:	172/289 - (59%)	Gaps:	11/289 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 LSQRAVTAT-----PQPPVTELD--DIFISVKTTKNYHDTRLALIIKTWFQLARDQTWFFTDTDD 188
            ||.|.:..|     |.|...||.  ||||.||||..:|.:||.|::.||....|.||:.|||:.|
  Rat    30 LSLRTMQGTLRLNQPNPGHLELQLGDIFIGVKTTWAFHRSRLDLLLDTWVSRTRQQTFIFTDSPD 94

  Fly   189 HYYQEKTKGHLINTKCSQGHFRKALCCKMSAELDVFLESGKKWFCHFDDDNYVNVPRLVKLLDEY 253
            ...||:...||:.|.||..|...||.|||:||.|.||.||.:||||.|||||||...|::||..:
  Rat    95 ELLQERLGSHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKALLQLLRTF 159

  Fly   254 SPSVDWYLGKPSISSPLEI-HLDSKNTTTNKKITFWFATGGAGFCLSRALTLKMLPIAGGGKFIS 317
            ....|.|:||||::.|:.. .|.|||.|  :.:.|||||||||||::|.|.|||:|.|.|..|:.
  Rat   160 PQDHDVYVGKPSLNRPIHASELQSKNRT--RLVRFWFATGGAGFCINRQLALKMVPWASGSHFVD 222

  Fly   318 IGDKIRFPDDVTMGFIIEHLLKVPLTVVDNFHSHLEPMEFIRQDTFQDQVSFSYAHMKNQWNVIK 382
            ....||.|||.|:|:|||..|...|.....||||||.::.:......:||:.||...:.:.|:||
  Rat   223 TSALIRLPDDCTVGYIIECKLGGRLQPSPLFHSHLETLQLLGTAQLLEQVTLSYGVFEGKLNIIK 287

  Fly   383 VDG-FDMKTDPKRFYSLHCQLFPYFSFCP 410
            :.| |..:.||.||.||||.|:|...:||
  Rat   288 LPGPFSHEEDPSRFRSLHCLLYPDTPWCP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fng	NP_524191.1	Fringe	145..394	CDD:190308	118/252 (47%)
Mfng	NP_954541.1	Fringe	51..300	CDD:190308	117/250 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348982
Domainoid	1	1.000	238	1.000	Domainoid score	I2221
eggNOG	1	0.900	-	-		E1_2C9I6
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3016
OMA	1	1.010	-	-		QHG47481
OrthoDB	1	1.010	-	-		D356445at33208
OrthoFinder	1	1.000	-	-		FOG0002392
OrthoInspector	1	1.000	-	-		otm46033
orthoMCL	1	0.900	-	-		OOG6_104952
Panther	1	1.100	-	-	O	PTHR10811
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1586
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770