DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fng and Mfng

DIOPT Version :9

Sequence 1:	NP_524191.1	Gene:	fng / 40314	FlyBaseID:	FBgn0011591	Length:	412	Species:	Drosophila melanogaster
Sequence 2:	NP_032621.1	Gene:	Mfng / 17305	MGIID:	1095404	Length:	321	Species:	Mus musculus

Alignment Length:	297	Identity:	138/297 - (46%)
Similarity:	179/297 - (60%)	Gaps:	10/297 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 TELARRSRNGELLRDLSQRAVTATPQPPVTELDDIFISVKTTKNYHDTRLALIIKTWFQLARDQT 180
            :.|::|...|.|  .|:||    .|.|...:|.||||:||||..:|.:||.|::.||....|.||
Mouse    28 SSLSQRMIQGAL--RLNQR----NPGPLELQLGDIFIAVKTTWAFHRSRLDLLLDTWVSRIRQQT 86

  Fly   181 WFFTDTDDHYYQEKTKGHLINTKCSQGHFRKALCCKMSAELDVFLESGKKWFCHFDDDNYVNVPR 245
            :.|||:.|...||:...||:.|.||..|...||.|||:||.|.||.||.:||||.|||||||...
Mouse    87 FIFTDSPDERLQERLGPHLVVTNCSAEHSHPALSCKMAAEFDAFLVSGLRWFCHVDDDNYVNPKA 151

  Fly   246 LVKLLDEYSPSVDWYLGKPSISSPLEI-HLDSKNTTTNKKITFWFATGGAGFCLSRALTLKMLPI 309
            |::||..:....|.|:||||::.|:.. .|.|||.|  |.:.|||||||||||::|.|.|||:|.
Mouse   152 LLQLLKTFPQDRDVYVGKPSLNRPIHASELQSKNRT--KLVRFWFATGGAGFCINRQLALKMVPW 214

  Fly   310 AGGGKFISIGDKIRFPDDVTMGFIIEHLLKVPLTVVDNFHSHLEPMEFIRQDTFQDQVSFSYAHM 374
            |.|..|:.....||.|||.|:|:|||..|...|.....||||||.::.:......:||:.||...
Mouse   215 ASGSHFVDTSALIRLPDDCTVGYIIECKLGGRLQPSPLFHSHLETLQLLGAAQLPEQVTLSYGVF 279

  Fly   375 KNQWNVIKVDG-FDMKTDPKRFYSLHCQLFPYFSFCP 410
            :.:.||||:.| |..:.||.||.||||.|:|...:||
Mouse   280 EGKLNVIKLPGPFSHEEDPSRFRSLHCLLYPDTPWCP 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fng	NP_524191.1	Fringe	145..394	CDD:190308	119/250 (48%)
Mfng	NP_032621.1	Fringe	51..300	CDD:190308	119/250 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845570
Domainoid	1	1.000	242	1.000	Domainoid score	I2217
eggNOG	1	0.900	-	-		E1_2C9I6
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	261	1.000	Inparanoid score	I3089
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47481
OrthoDB	1	1.010	-	-		D356445at33208
OrthoFinder	1	1.000	-	-		FOG0002392
OrthoInspector	1	1.000	-	-		otm43945
orthoMCL	1	0.900	-	-		OOG6_104952
Panther	1	1.100	-	-	O	PTHR10811
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1586
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.770