DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32432 and lrp10

DIOPT Version :9

Sequence 1:	NP_649266.1	Gene:	CG32432 / 40310	FlyBaseID:	FBgn0052432	Length:	1307	Species:	Drosophila melanogaster
Sequence 2:	XP_688859.4	Gene:	lrp10 / 560361	ZFINID:	ZDB-GENE-140418-2	Length:	748	Species:	Danio rerio

Alignment Length:	294	Identity:	64/294 - (21%)
Similarity:	100/294 - (34%)	Gaps:	74/294 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   202 NLQL--APGSSSTGCSLAE---FSCSNGRCVPLSKYCNNLNDCGDGSDEPRFCTRCNRTY----- 256
            |.||  ..|:....|::.:   |.|.:.|||..|..|:...||.||:||    ..|..|.
Zfish   410 NYQLNCPDGTDERECTICQPGTFHCDSDRCVFESWRCDGQVDCKDGTDE----LNCTATLPRKVI 470

  Fly   257 -YGDIGQTYALELHRPKQDRVPFVCVLTFTAAGGQHGDVVQVTLDSFTI-----GRFTSYVHEGC 315
             ...:|.               .||.|....|.|....:..:....:::     .:....:.:..
Zfish   471 TAATVGS---------------LVCGLLLVIAMGCTCKLYSLRTREYSLFAPITRQEAELIQQQA 520

  Fly   316 PDGYMQ-IAESARTPIGGMWCGSSWGPVLFYSETRSLIFTIR-LNRLARDQSGYNFDFRIRYKVL 378
            |..|.| ||:....|:...       |....:||.||  ::| :.:|.|..:..:...|.|.:.:
Zfish   521 PPSYGQLIAQGIIPPVEDF-------PTENPNETVSL--SLRGILQLLRQDNASSLRRRRRPRFV 576

  Fly   379 SRD-SSVTRYGGIKLAELAQWHNRSSFLNQQQQQQQQQQQQQQQQQGAPGILEDFTNSSVARSDR 442
            .|. ..:.|:|.|..|........:|    ..||.:......|..|.:||.      ||||
Zfish   577 RRAVRRLRRWGLIPRATSRPTQTTAS----SSQQTEAANSSTQPSQSSPGA------SSVA---- 627

  Fly   443 YGQDFSLFSAYANNKTFMASLEKSLAKDEQNYTE 476
                         .:.|..||.:.|...:|..|:
Zfish   628 -------------TEAFSQSLTQKLGLSQQTETQ 648

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32432	NP_649266.1	LDLa	214..245	CDD:197566	12/33 (36%)
		CUB	503..646	CDD:238001
		LDLa	1203..1231	CDD:197566
lrp10	XP_688859.4	CUB	36..136	CDD:238001
		LDLa	142..181	CDD:238060
		CUB	229..334	CDD:294042
		LDLa	427..461	CDD:238060	13/37 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900