DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32432 and CD320

DIOPT Version :9

Sequence 1:	NP_649266.1	Gene:	CG32432 / 40310	FlyBaseID:	FBgn0052432	Length:	1307	Species:	Drosophila melanogaster
Sequence 2:	NP_057663.1	Gene:	CD320 / 51293	HGNCID:	16692	Length:	282	Species:	Homo sapiens

Alignment Length:	287	Identity:	64/287 - (22%)
Similarity:	93/287 - (32%)	Gaps:	107/287 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 LTLLLCLGISLGMAATAAAAGGGGGGGGGAAPVSGSGAAGFPSSSSSISSSLGPGKPVNLQLAPG 208
            |.|||.||:.||:.|.|:                       |.|:.:.:.:.||
Human    19 LALLLLLGLGLGLEAAAS-----------------------PLSTPTSAQAAGP----------- 49

  Fly   209 SSSTGCSLAEFSC-SNGRCVPLSKYCNNLNDCGDGSDEPRF----CTRCNRTYYGDIGQTYALEL 268
             ||..|...:|.| ::|.||||:..|:...||.|||||...    ||:        .||.
Human    50 -SSGSCPPTKFQCRTSGLCVPLTWRCDRDLDCSDGSDEEECRIEPCTQ--------KGQC----- 100

  Fly   269 HRPKQDRVPFVCVLTFTAAGGQHGDVVQVTLDSFTIGRFTSYVHEGC-P-----DGYMQIAESAR 327
              |....:|..|......:||....:...:..:...|.....:.:.| |     ||:....:|:
Human   101 --PPPPGLPCPCTGVSDCSGGTDKKLRNCSRLACLAGELRCTLSDDCIPLTWRCDGHPDCPDSS- 162

  Fly   328 TPIGGMWCG----------SSWGPVLFYSETRSLIFTIRL----------------NRLARDQSG 366
               ..:.||          ::.||.:......||.....:                :..|.||||
Human   163 ---DELGCGTNEILPEGDATTMGPPVTLESVTSLRNATTMGPPVTLESVPSVGNATSSSAGDQSG 224

  Fly   367 YNFDFRIRYKVLSRDSSVTRYGGIKLA 393
                            |.|.||.|..|
Human   225 ----------------SPTAYGVIAAA 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32432	NP_649266.1	LDLa	214..245	CDD:197566	14/31 (45%)
		CUB	503..646	CDD:238001
		LDLa	1203..1231	CDD:197566
CD320	NP_057663.1	LDLa	54..89	CDD:238060	16/34 (47%)
CD320	NP_057663.1	LDLa	132..167	CDD:238060	6/38 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900