Protein Alignment CG32432 and Lrp12

DIOPT Version :10

• Sequence 1: NP_649266.1
• Gene: CG32432 / 40310
• FlyBaseID: FBgn0052432
• Length: 1307
• Species: Drosophila melanogaster
• Sequence 2: NP_001128355.1
• Gene: Lrp12 / 314941
• RGDID: 1304943
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 983
• Identity: 185/983 - (18%)
• Similarity: 302/983 - (30%)
• Gaps: 382/983 - (38%)

  Fly   481 LGDLIPGTYCSRIFSDCDKKPCRLQ-------SPNFPGIYPRNLTCYYAVRQH------------ 526
            |.:|....:.|.:.:.|.:.|.:::       ||.:|..||..:.|.:.:|.:
  Rat    31 LAELSENVHISGVSTACGETPEQIRGPTGIITSPGWPSDYPAKINCSWLIRANPGEIITISFQDF 95

  Fly   527 DVPHGKHALILVKQPKGNLVWISTQET-------AAANKMAPPPSASDKDKKFEPRLKTWNYCDY 584
            |:...:..         .|.|: |.||       .|.....|||..|.
  Rat    96 DIQGSRRC---------TLDWL-TIETYKNIESYRACGSTIPPPYISS----------------- 133

  Fly   585 IQENVKPKWKSTDYVT------VYDGYTTRDPIIL--KF-CGGGQAVPAA----------VSSGP 630
             |::|..::.|.|.|:      .|....:.:|...  :| ||.|:.:|.|          .||..
  Rat   134 -QDHVWIRFHSDDSVSRKGFRLAYFSGKSEEPHCACDQFRCGNGKCIPEAWKCNSMDECGDSSDE 197

  Fly   631 ELLVEFSTSPFGTFTGTSSQVLPLYGFQ------------------------LEVEVQFVDIQSP 671
            |:.|:.:..|    |.|:.|......||                        |::..: :|...|
  Rat   198 EVCVQDAHPP----TTTAFQPCAYNQFQCLSRFTKVYTCLPESLKCDGNIDCLDLGDE-IDCDMP 257

  Fly   672 TYSKNKKPCEFWIRGAGRGILESPKHS--LAPNSTCLYHLQGLGVFKTFDHLSLSRRTSSQSGMH 734
            |       |..|:: ...|...||.:.  ..|.|.|.:      :..|.||..:
  Rat   258 T-------CGQWLK-YFYGTFSSPNYPDFYPPGSNCTW------LIDTGDHRKV----------- 297

  Fly   735 QPLSRFKVWISVLKFNLDPEFGQIDETSVGAIGVLQTQEDCSGMLRIWDGTLRDAPVCKDLNCAT 799
                       :|:|.   :| ::|.|..|            ..::|:|| |.:.| .|.|...|
  Rat   298 -----------ILRFT---DF-KLDGTGYG------------DYVKIYDG-LEENP-RKLLRVLT 333

  Fly   800 ETSSYNTLG----------HYT---------HNSTSVIARFCRG------------TIPRTCD-- 831
            ...|:..|.          |:.         .|:|..:..||..            |..:.||
  Rat   334 AFDSHAPLTVVSSSGQIRVHFCADKVNAARGFNATYQVDGFCLPWEIPCGGNWGCYTEQQRCDGY 398

  Fly   832 ------RSNINETYARPCTISESYVSTSDAITLELRNTESTVLRPLDFKLKYEFIDLHQDGLPWG 890
                  |..||      ||:.:..         |...:.:.|..|...:..|      |:..|.|
  Rat   399 WHCPNGRDEIN------CTMCQKE---------EFPCSRNGVCYPRSDRCNY------QNHCPNG 442

  Fly   891 GGEHDC------------NR-KFLSSMMDRKD---------------------PAIFRSV--RNI 919
            ..|.:|            || .|.|.:.|.:|                     .|:..|:  ..:
  Rat   443 SDEKNCFFCQPGNFHCKNNRCVFESWVCDSQDDCGDGSDEESCPVIVPTRVITAAVIGSLVCGLL 507

  Fly   920 FLFGRGGTRNLKCIYKFEAQRGER--VRIKMRKVTTTNRPCYSRV--------DEDI-----NRS 969
            .:...|.|..|..:..||.:..|.  .|::...:.....|.|.::        .||.     |::
  Rat   508 LVIALGCTCKLYSLRMFERRSFETQLSRVEAELLRREAPPSYGQLIAQGLIPPVEDFPVCSPNQA 572

  Fly   970 FC-----------YGDTNVRI-------EIFERPYHDSILLHRGCMCNSSNQSHLPVEYTSTSRD 1016
            ..           .|..::|:       .|:.|.::.:...|.|.:...|......|...|:||:
  Rat   573 SVLENLRLAVRSQLGFPSIRLPMTGRSRNIWNRIFNFARSRHSGSLALVSGDGDEVVPSQSSSRE 637

  Fly  1017 VE---VH---FIAQNMTTLDDPDTVN----FEGMFEFVKAPTSCKDGRRKFGPSGTIDMTF---G 1068
            .|   .|   |.|::    ||.||.|    ..|....|.||..     :|..|:..::.|.   |
  Rat   638 TERSHPHRSLFSAES----DDTDTENERRDTAGASGGVAAPLP-----QKVPPTTAVEATVGTGG 693

  Fly  1069 DVECRSRPWLIEPSNGNKFLYVRLKAIFLSKHNPTQTLNATYVQTDTWRCETKSRAVLTTSEGLT 1133
            :...:|...  ..::|.:...|...::..::|..|..|:                   ..::||.
  Rat   694 NSSAQSTRG--GHADGREVSSVEAPSVSPARHQLTSALS-------------------RMTQGLR 737

  Fly  1134 IVACPLSPDSNAYEFVEIFSSGWNERP----NFALVNRSRAISVEFLRP-GNGEYSFNWMELIPR 1193
            .|...|...|         |:..|..|    :..:..|.....||.|.| .:|....:..| ..|
  Rat   738 WVRFTLGRSS---------STNQNRSPLRQLDTGVSGREDDDDVEMLIPVSDGASDIDANE-CSR 792

  Fly  1194 PTLSMAED------------------------CQFKC-----AEL-GACVNASVWCDGVVHCPSG 1228
            |.|.:|.|                        |: :|     |:: ..|:.|:|..:.   |
  Rat   793 PLLDLASDQVQGFRQPHSSGNPGARTSNRDGPCE-RCGIVHTAQIPDTCLEAAVKTEA---C--- 850

  Fly  1229 DDETFLQC 1236
            |||..|.|
  Rat   851 DDEALLLC 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32432	NP_649266.1	LDLa	214..245	CDD:197566
		CUB	503..646	CDD:238001	36/187 (19%)
		LDLa	1203..1231	CDD:197566	7/33 (21%)
Lrp12	NP_001128355.1	CUB	47..158	CDD:238001	26/138 (19%)
		LDLa	166..200	CDD:238060	9/33 (27%)
		LDLa	215..254	CDD:238060	3/39 (8%)
		CUB	267..371	CDD:238001	28/149 (19%)
		LDLa	413..448	CDD:238060	8/49 (16%)
		LDLa	451..485	CDD:238060	6/33 (18%)